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Summary Expression Gene Literature (60) GO Terms (32) Nucleotides (252) Proteins (46) Interactants (1114) Wiki
XB-GENEPAGE-485062
Gene Symbol:
gata6

Gene Name:
GATA binding protein 6

Synonyms:
GATA-6 , XGATA-6 , XGATA6 , tGata6 , gata6b , gata6a , gata6-b , gata6-a ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger transcription factor

Protein Function :
Transcriptional activator that binds 5'-GATA-3'-containing motifs within gene promoters. Regulates cardiac-specific transcription during embryogenesis and thereby cardiogenesis.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
atrioventricular septal defect [+]

OMIM:
CONOTRUNCAL HEART MALFORMATIONS; CTHM [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-485063 XB-GENE-865113 XB-GENE-6252341
Gene Symbol gata6 gata6.L gata6.S
Chromosome Chr06 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 395062
399082
397845
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gata6 gata6.L gata6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GATA6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gata6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gata6 Ensembl
zebrafish
ZFIN, AGR gata6 ZFIN Ensembl
chicken
GEISHA GATA6 Ensembl
fruit fly
worm
Publications
First The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis., Dev Biol 1996            
Most Recent Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation., Cell Rep 2019                            
All View All Papers 16 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 7 terms 5 terms
PANTHER gata6
KEGG Pathways K17897 K17897 K17897
KOG [K] GATA-4/5/6 transcription factors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gata6
Morpholinos gata6 MO1 , gata6 MO2 gata6 MO1 , gata6 MO2 gata6 MO1 , gata6 MO2
Clones EXRC Horizon Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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