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Summary Expression Gene Literature (51) GO Terms (25) Nucleotides (240) Proteins (31) Interactants (1030) Wiki
XB-GENEPAGE- 485062

Gene Symbol: gata6

Gene Name: GATA binding protein 6

Synonyms: GATA-6 , XGATA-6 , XGATA6 , tGata6 , gata6b , gata6a , gata6-b , gata6-a
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger transcription factor

Protein Function :
Transcriptional activator that binds 5'-GATA-3'-containing motifs within gene promoters. Regulates cardiac-specific transcription during embryogenesis and thereby cardiogenesis.


Interactants: Loading ...

Disease Ontology:
   ATRIOVENTRICULAR SEPTAL DEFECT [+]

OMIM Diseases:
   CONOTRUNCAL HEART MALFORMATIONS; CTHM [+]
1/5
 

Xenbase Gene ID XB-GENE-485063 XB-GENE-865113 XB-GENE-6252341
Gene Symbol gata6 gata6.L gata6.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene [+] Xl.183 Xl.23009
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 79 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gata6 gata6.L gata6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GATA6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gata6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR gata6 ZFIN Ensembl
chicken
GEISHA GATA6 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. [Dev Biol 1996]
Most recent: Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis. [Dev Biol 2018]
View All Papers 15 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 8 terms 6 terms
PANTHER gata6
KEGG Pathways K17897 K17897 K17897
KOG [K] GATA-4/5/6 transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 4 clone(s) EXRC - 1 clone(s) EXRC - 4 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino gata6 MO1 , gata6 MO2 gata6 MO1 , gata6 MO2 gata6 MO1 , gata6 MO2
Affymetrix 1.0 Str.6139.1.S1_at [+] Xl.183.1.S1_at Xl.23009.1.S1_at
Affymetrix 2.0 Xl2.183.1.S1_at Xl2.23009.1.S1_at [+]

Symbol legend[+]
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Version: 4.9.1
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