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Summary Expression Gene Literature (151) GO Terms (10) Nucleotides (96) Proteins (38) Interactants (1023) Wiki
XB-GENEPAGE-485440
Gene Symbol:
pitx1

Gene Name:
paired like homeodomain 1

Synonyms:
X-PITX-1 , xPitx1 , Xpitx-1 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies an...[+]



Interactants:
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Diseases: 


Disease Ontology:
clubfoot

OMIM:
LIEBENBERG SYNDROME; LBNBG [+]

External Links:
GEO Series :
GSE111454.
1/5
 
Xenbase Gene ID XB-GENE-485441 XB-GENE-485445 XB-GENE-17330607
Gene Symbol pitx1 pitx1.L pitx1.S
Chromosome Chr3 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 493226
394310
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pitx1 pitx1.L pitx1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PITX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pitx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pitx1 Ensembl
zebrafish
ZFIN, AGR pitx1 ZFIN Ensembl
chicken
GEISHA PITX1 Ensembl
fruit fly
worm
Publications
First The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping., Development 1999              
Most Recent Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis., Dev Growth Differ 2018                
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 6 terms 0 term
PANTHER pitx1
KEGG Pathways K09356 K09356
KOG [K] Transcription factor PTX1, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pitx1
Morpholinos pitx1 MO1 , pitx1 MO2 pitx1 MO1 , pitx1 MO2 pitx1 MO1 , pitx1 MO2
ORFs pitx1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list