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Summary Expression Gene Literature (65) GO Terms (15) Nucleotides (47) Proteins (26) Interactants (194) Wiki
XB-GENEPAGE-485833
Gene Symbol:
tlx1

Gene Name:
T cell leukemia homeobox 1

Synonyms:
Xhox11 , XHox11L2 , hox11 , hox11-a ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :


InterPro :
TLX1/2/3 , Homeobox dom , Homeobox metazoa , Homeobox CS [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-485834 XB-GENE-865464 XB-GENE-17331684
Gene Symbol tlx1 tlx1.L tlx1.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100494864
373832
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tlx1 tlx1.L tlx1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TLX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tlx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tlx1 Ensembl
zebrafish
ZFIN, AGR tlx1 ZFIN Ensembl
chicken
GEISHA TLX1 Ensembl
fruit fly
worm
Publications
First HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint., Nature 1997  
Most Recent KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis., Development 2017                            
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 7 terms 0 term
PANTHER tlx1
KEGG Pathways K09340
KOG [R] Transcription factor BarH and related HOX domain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tlx1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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