Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (24) GO Terms (36) Nucleotides (189) Proteins (83) Interactants (558) Wiki
XB-GENEPAGE-485974
Gene Symbol:
tcf7l2

Gene Name:
transcription factor 7 like 2

Synonyms:
tcf4 , XTCF-4 , tcf4e ( Add synonyms , Nomenclature history )

Gene Function:
high mobility group transcription factor

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
type 2 diabetes mellitus

OMIM:
DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM

External Links:
1/3
 
Xenbase Gene ID XB-GENE-485975 XB-GENE-485979 XB-GENE-17341027
Gene Symbol tcf7l2 tcf7l2.L tcf7l2.S
Chromosome Chr7 chr7L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100101719
399164
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tcf7l2 tcf7l2.L tcf7l2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TCF7L2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tcf7l2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tcf7l2 Ensembl
zebrafish
ZFIN, AGR tcf7l2 ZFIN Ensembl
chicken
GEISHA TCF7L2 Ensembl
fruit fly
worm
Publications
First TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs., Mech Dev 1998  
Most Recent Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles., Sci Rep 2020                    
All View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 36 terms 7 terms 0 term
PANTHER tcf7l2
KEGG Pathways K04491 K04491
KOG [K] Transcription factor TCF-4
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tcf7l2
Antibodies tcf7l2 Ab1 tcf7l2 Ab1 tcf7l2 Ab1
Morpholinos tcf7l2 MO1 , tcf7l2 MO2 , tcf7l2 MO3 tcf7l2 MO1 , tcf7l2 MO2 , tcf7l2 MO3 tcf7l2 MO1 , tcf7l2 MO2 , tcf7l2 MO3
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556