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Summary Expression Gene Literature (9) GO Terms (7) Nucleotides (1013) Proteins (59) Interactants (255) Wiki
XB-GENEPAGE-486273
Gene Symbol: c3

Gene Name: complement component 3

Synonyms: ccc3 ( Add synonyms , Nomenclature history )

Gene Function: activation of complement

Protein Function :
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b c...[+]

Interactants: Loading ...
Disease Ontology: age related macular degeneration 9 [+]

OMIM Diseases: MACULAR DEGENERATION, AGE-RELATED, 9; ARMD9 [+]

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Xenbase Gene ID XB-GENE-486274 XB-GENE-864831 XB-GENE-17335280
Gene Symbol c3 c3.L c3.S
Chromosome Chr03 Scaffold175714
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine c3 c3.L c3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards C3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR C3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR c3a.1 c3a.2 ZFIN Ensembl
chicken
GEISHA C3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Novel gene expression domains reveal early patterning of the Xenopus endoderm., Gene Expr Patterns 2003              
Most Recent The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development., Dev Cell 2016                                                    
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 7 terms 0 term
PANTHER c3
KEGG Pathways K03990 K03990
KOG [O] Alpha-macroglobulin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino c3 MO1 c3 MO1 c3 MO1
Affymetrix 1.0 Str.2323.4.A1_at [+] Xl.2209.1.S1_at [+]
Affymetrix 2.0 Xl2.44891.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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