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Summary Expression Gene Literature (10) GO Terms (18) Nucleotides (1023) Proteins (62) Interactants (321) Wiki
XB-GENEPAGE-486273
Gene Symbol:
c3

Gene Name:
complement C3

Synonyms:
ccc3 ( Add synonyms , Nomenclature history )

Gene Function:
activation of complement

Protein Function :
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b c...[+]


InterPro :
Histone-fold , CENP-T/H4 C , Histone H4 , Histone H4 CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
age related macular degeneration 9 [+]

OMIM:
MACULAR DEGENERATION, AGE-RELATED, 9; ARMD9 [+]

External Links:
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Xenbase Gene ID XB-GENE-486274 XB-GENE-864831 XB-GENE-17335280
Gene Symbol c3 c3.L c3.S
Chromosome Chr3 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100216255
398666
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine c3 c3.L c3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards C3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR C3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR C3 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR c3a.1 c3a.2 ZFIN Ensembl
chicken
GEISHA C3 Ensembl
fruit fly
worm
Publications
First Novel gene expression domains reveal early patterning of the Xenopus endoderm., Gene Expr Patterns 2003              
Most Recent Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis., Aquat Toxicol 2020  
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 7 terms 0 term
PANTHER c3
KEGG Pathways K03990 K03990
KOG [O] Alpha-macroglobulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks c3
Morpholinos c3 MO1 c3 MO1 c3 MO1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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