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Summary Expression Gene Literature (122) GO Terms (1) Nucleotides (124) Proteins (28) Interactants (579) Wiki
XB-GENEPAGE- 486295

Gene Symbol: fst

Gene Name: follistatin

Synonyms: xfs , follistatin , foll
Add Xenopus synonyms , Nomenclature history


Gene Function: activin and bmp7 antagonist, also antagonizes bmp2/4 but less effectively

Protein Function:
Binds directly to activin and functions as an activin antagonist which plays a role in neural induction. The short isoform is a more potent inhibitor of activin than the long isoform. Specific inhibito...[+]


Interactants: YYY

OMIM Disease Associations: POLYCYSTIC OVARY SYNDROME 1; PCOS1
 
Xenbase Gene ID XB-GENE-486296 XB-GENE-486300 XB-GENE-17338212
Gene Symbol fst fst.L fst.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10666 Xl.1094 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 11 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine fst fst.L fst.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FST OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Fst MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN fsta fstb ZFIN Ensembl
chicken
GEISHA FST Ensembl
fruit fly
FLYBASE Fst Ensembl
worm
WORMBASE
Publications
First: Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis. [Biochem Biophys Res Commun 1991]
Most recent: SMOC can act as both an antagonist and an expander of BMP signaling. [Elife 2017]
View All Papers 11 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 1 terms 0 term
EC
PANTHER fst
KEGG Pathways K04661 K04661 K04661
KOG [R] FOG: Kazal-type serine protease inhibitor domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino fst MO1 , fst MO2 , fst MO3 fst MO1 , fst MO2 , fst MO3 fst MO1 , fst MO2 , fst MO3
ORF fst ORF1
Affymetrix 1.0 Str.10666.1.S1_at Xl.1094.1.S1_at
Affymetrix 2.0 Xl2.1094.2.S1_a_at

Symbol legend[+]

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