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Summary Expression Gene Literature (25) GO Terms (17) Nucleotides (136) Proteins (31) Interactants (446) Wiki
XB-GENEPAGE- 486693

Gene Symbol: hey1

Gene Name: hes related family bHLH transcription factor with YRPW motif 1

Synonyms: hrt1 , XHRT1 , chf2 , hrt-1 , hesr1 , herp2 , oaf1 , bc8
Add Xenopus synonyms , Nomenclature history


Gene Function: helix-loop-helix transcription factor/transcriptional repressor

Protein Function:
Downstream effector of Notch signaling. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Acts as a suppressor of neurogenesis by antagonizing proneural...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/4
 
Xenbase Gene ID XB-GENE-486694 XB-GENE-17344247 XB-GENE-865637
Gene Symbol hey1 hey1.L hey1.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq Swiss-Prot NCBI Protein TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.11458 [+] Xl.469 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 65 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine hey1 hey1.L hey1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HEY1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hey1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN hey1 ZFIN Ensembl
chicken
GEISHA HEY1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Microinjection of purified ornithine decarboxylase into Xenopus oocytes selectively stimulates ribosomal RNA synthesis. [Proc Natl Acad Sci U S A 1983]
Most recent: A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. [Nucleic Acids Res 2016]
View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 5 terms 17 terms
EC
PANTHER hey1
KEGG Pathways K09091 K09091 K09091
KOG [K] Transcriptional repressors of the hairy/E(spl) family (contains HLH)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino hey1 MO1 , hey1 MO2 hey1 MO1 , hey1 MO2 hey1 MO1 , hey1 MO2
ORF hey1 ORF1
Affymetrix 1.0 Str.11458.1.S1_at [+] Xl.469.1.S1_at [+]
Affymetrix 2.0 Xl2.469.1.S1_at [+]

Symbol legend[+]

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