Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (568) GO Terms (11) Nucleotides (162) Proteins (57) Interactants (1846) Wiki
XB-GENEPAGE-486770
Gene Symbol:
gsc

Gene Name:
goosecoid homeobox

Synonyms:
Xgsc , goosecoid , gsc-a , gsc-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Plays a central role in executing Spemann's organizer phenomenon (the dorsal blastopore lip of the early Xenopus laevis gastrula can organize a complete secondary body axis when transplanted to another...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA, AND SKELETAL ABNOR

External Links:
1/6
 
Xenbase Gene ID XB-GENE-486771 XB-GENE-6252605 XB-GENE-864870
Gene Symbol gsc gsc.L gsc.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549458
397752
397748
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq NCBI Protein RefSeq Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine gsc gsc.L gsc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GSC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gsc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gsc Ensembl
zebrafish
ZFIN, AGR gsc ZFIN Ensembl
chicken
GEISHA GSC Ensembl
fruit fly
FLYBASE Gsc Ensembl
worm
Publications
First Molecular nature of Spemann''s organizer: the role of the Xenopus homeobox gene goosecoid., Cell 1991                
Most Recent Natural size variation among embryos leads to the corresponding scaling in gene expression., Dev Biol 2020                      
All View All Papers 113 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 14 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 4 terms 4 terms
PANTHER gsc
KEGG Pathways K09324 K09324 K09324
KOG [K] Transcription factor PHOX2/ARIX, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks gsc
Morpholinos gsc MO1 gsc MO1 gsc MO1
ORFs gsc.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556