Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (163) GO Terms (29) Nucleotides (101) Proteins (38) Interactants (839) Wiki
XB-GENEPAGE-487097
Gene Symbol: gsk3b

Gene Name: glycogen synthase kinase 3 beta

Synonyms: gsk3 , gsk-3 , Xgsk-3 , gsk3beta , gsk3-beta ( Add synonyms , Nomenclature history )

Gene Function: serine/threonine kinase, wnt signal transduction

Protein Function :
Plays a role in the organization of the formation of the main body axis of developing embryo. Acts as an inhibitor of differentiation of primary neurons. Inhibits the ability of ectopically expressed N...[+]


Interactants: Loading ...
 
Xenbase Gene ID XB-GENE-487098 XB-GENE-865674 XB-GENE-17333303
Gene Symbol gsk3b gsk3b.L gsk3b.S
Chromosome scaffold_367 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100489648
Entrez Gene: 399097
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine gsk3b gsk3b.L gsk3b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GSK3B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gsk3b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR gsk3ba gsk3bb ZFIN Ensembl
chicken
GEISHA GSK3A Ensembl
fruit fly
worm
WORMBASE
Publications
First Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3., Development 1995                
Most Recent Ca2+/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down., EMBO J 2018  
All View All Papers 17 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 12 terms 0 term
PANTHER gsk3b
KEGG Pathways K03083
KOG [G] Glycogen synthase kinase-3
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon
Antibody Gsk3a/b Ab1 Gsk3a/b Ab1
Morpholino gsk3b MO1 gsk3b MO1 gsk3b MO1
ORF gsk3b.L ORF1
Affymetrix 1.0 Str.35858.1.A1_at Xl.324.1.S1_at [+]
Affymetrix 2.0 Xl2.324.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.2


Major funding for Xenbase is provided by grant P41 HD064556