hhex Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (70)

Nucleotides (101)

Interactants (365)

XB-GENEPAGE-487158

Gene Symbol: hhex Gene Name: hematopoietically expressed homeobox Synonyms: XHex, tHex, hex Add Xenopus synonyms Gene Function: homeodomain transcription factor Interactants: cer1(24) , chrd(16) , t(15) , bmp4(13) , gsc(13) , ins(13) , pdx1(13) View All	1/6

XB-GENE-487159

XB-GENE-865680

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_204089\|Xenopus (Silurana) tropicalis hematopoietically expressed homeobox (hhex), mRNA ATTACAGCAGGATCCGAGTGTGGGAGAGAGAGAATAGCCATGCAGTACCAGCACCCCAGCTCCTCAGCCCTGGGGCTCAGTGTCCCCCTGTACGCACCCACCCCTCTGCAGCCAGTGCACCCAACTCCCTTCTACATTGATGATATCCTGGGAAGGAGCAGCGCCTCTAATGGGACCCCAGCCTTACCCACCCCAACCCTGCCATCGCCCAACTCTTCCTTCACCAGCCTGGTGGCTACCTACAGGACTCCCATCTATGAGCCTACTCCCATTCACCCTGCCTTCACCCACCCCGGGGCAGCCCTGGCAGCTTCCTATGGAGCCAGCACCTATGCCAACCCTCTGTACCCCTTCTCCAGGCCGGTCAGCGAGTACACCCATGCCCTCATCCGGCACGACACCCTGGGCAAACCCTTGCTATGGAGCCCCTTCATCCAGAGGCCTCTTCACAAGCGGAAAGGCGGCCAAGTGCGGTTTTCAAACGATCAGACCATCGAATTAGAGAAAAAGTTTGAGACACAAAAATATTTATCGCCCCCGGAAAGGAAACGCCTGGCTAAAATGCTTCAGCTCAGCGAGAGACAGGTCAAAACCTGGTTCCAGAACAGAAGAGCCAAATGGAGGCGTCTCAAGCAGGAAAACCCACAGGGAAATAAGAAAGACGAAACTGAAAGTCTAGAGAATATCTGCGAAGAGAGTCAGGAGAGGTGTTTGAGTGCTGAGCAGAAGAGCAGAGAGTCCTCCTTGGATGAACCCACCTCATCGCCCACCTCCCAAGAGACTCTGGATTCAGAGGTGTCCGATGATTCCGACCAGGAGGTGGACATTGAAGGAGACAAAGGATTTTACAACTGTGCACATTAACTGCTGCTCAGTAAGAATGGACCTCTCTTCAGCTTGCACTTTAACAGAAGCTGGACCTAGCTCCCTGGTAGCCTGACTTGGGTTAAGCCAGTGGCTGTCGGACTTTCTCAGTTCAAGCCCCCACTGGAGTTCCAACCTTTGTTCAGGGCCCCCTCAGCTCATAACAAGGAAAGCAGCGGTGTACCAGTCAGAGCAGAAAATACATTTTTATCCCAAATCTTATCCTAATTAACCTTCAAGTTGGAGGTATCTAGGAGAGCAAGTAGGCATTCTCCTCAAATTTCATTCTTTATTGACCTTTCAGGTGTATTTAGGAGAGCAAATAGGCATCCTCCCTAATTCTCACCCTAACTGGCAAGCTTCTATCCCACAGTGGCACAGTTTGGGAACCACTGAGTTAAGGGGATGGAAAGGACATTTTATCAATGTATATCAAGGTTTAGTTTGATCATGGTCAAAGTTCTATTTCAGATTGTGTATTTATCATAAACGGTGTTACTGTAATATTTTGCCTAATTGCACAATACCACTAATATTCCCCAAGTGCCTTTTTTATACAGGTAGATCAGGAATCTCATTGTGTAAGAAAGCTCAGATTTTATTGACACTCAAAAATGAAGGAAGTTTTGTGTATAAATTCCAGTGCATCTCAGGTTGGGGTGGCCAGGCCTATTGTTTGAGTGGCTTGGGAATTTCCCCTATGTACACAAGCAAACTGTCAATCATGGAGGGTGCACAGCCAATGAGGTCGCAAACAGGCAACCCATTTCACGCGGACCATATGGACAGCCCTTTTATGGGGTACAATTCATATTCCCTTATTGCTCCATTGTCTATAAATGACTTTAGGCTTACATAACTATATTGTTGGGTCTATTTGGAATGGAAAAATAAATATTAAAAGAAGCTTAATTTAGCAATAATTAAAATTTTACATATTTGTACATAATTCTTTTTGTAAATCCCAAGTGCATTGAGAAAATTGCCAAATAATGATTTTTTTTTTTACAAAGGGAGATCTCAAATCAAATGTTATTATATGATTTTTTTATTGTGAATATGTAATATATACATTGTTCTTTTTGTATAATGCGTGTGTTGTTGTTATACCTCAGGTTGTTTATATGTCTTGTAAATATATTTTCATCATCCAAGCAAAAAACATATTTAATTTTGTGTCTTAAAAAAACAGTGGAATAAAAGAAAAAAATGGATACACAAAAA	Refseq >NM_001085590\|Xenopus laevis hematopoietically expressed homeobox (hhex), mRNA ATCTCTCCGCACGGACGCGCCAAGGGACATTTAAGAAGAGTGTGGCCCCAGTGTCAGGCAGATCATCTTATATCGGTGGATTATATCGGATCTGAGTGTGGAAAGAGGAATCGACATGCAGTACCAGCACCCCAGCTCCTCAGCTCTGGGGCTCAGTGTCCCCCTGTTCGCTCCCACCCCTCTGCAGCACCCAACTCCCTTCTACATTGATGATATCCTGGGAAGGAACAGCGCATCTAATGGGACCCCAGCCTTACCCACCCCAACCCTGCCATCTCCCAACTCATCCTTCACCAGCCTGGTGGCTACTTACCGGACTCCCATCTATGAGCCTACTCCCATTCACCCTGCCTTCACCCACCCAGGGGCAGCCCTAGCAGCTTCCTATGGAGCCAGCACCTATGCCTCCCCTCTGTACCCCTTCTCCAGGCCAGTCAGCGACTACACCCACGCCCTCATCCGACACGACTCTCTGGGCAAACCCCTGCTCTGGAGCCCCTTCATCCAGAGGCCTCTGCACAAGCGGAAAGGAGGACAAGTGAGGTTTTCCAACGATCAAACCATTGAGTTGGAGAAAAAATTCGAGACGCAAAAATATTTATCGCCCCCTGAGAGGAAGCGACTGGCTAAAATGCTGCAGCTCAGCGAGAGACAGGTCAAAACCTGGTTCCAGAACAGAAGAGCCAAATGGAGGCGTCTCAAGCAGGAGAACCCACAGGGAAATAAGAAAGACGAAACCGAAAGTCTAGAAAATATCTGCGAAGAGAGTCAGGAGAGGTGTTTGAGCGCCGAGCAGAAGAGCAGAGAGTCCTCCCTGGATGATCCCACCTCGTCGCCCACCTCTCAAGGGAACCTGGATTCGGAGGTGTCTGACGATTCCGACCAGGAGGTGGACATTGAAGGCGACAAAGGATATTACAACTGTGCACATTAACAAAATGGACCTCTATTCAGCTTGCACTTTAACAGAAGCTGGACCTAGCTCCCTGGAGACTTGGGTTAAGGCAGGGTTTGTCAGACTTTTTTTCAGTTCAAACCCCCATTGGAGTCCCAACCCTTGTTCAGGAACCCCTTAGTTCATGACAATATTACAGATATAGTAAAACAGCAGTGTATCAGTCATTCAACCATAATTCTAAAAATATTTACACAAAACTAAATTTTCACCCCTTCATCCAATTTAACCTTCAAGGTGGAGGTTTTCTAGGAGAATACATAGGCATTCACCTAAATTCTCACCCTAACTGGCCTTGAGGCTTATGCTTAGTGTCGGACTGGGGTGTCCGGAGCCCACTGGGTCGTGAGCTTCAGCTCCTTCAAACATTGCCCCTCCTTTTGGCTGCGATCTGGGTCGGCAGGAACTGCAGGGGGCCCAAAGGGACAGTCCAACCCTCGCTATGCTTCAATCTCCTCCCAGGGATGGCAGTCCTAAAGTTTGGGAAGGAGTGCAAAGGACATTTTATAGGTGACAATGTCTGATCATGGTCAATGTTCTATTTCAGATTGTGTATTTATCATAAAAGATATTACTGTAATATTTTGACTAATTGCACAATATCACTGATATTCCCAAGTGCCTTTTTTAAAAAAATACAGGCAGATAGGAATATCATTGTGTAAGAAAGCTCAGATTATATTGACACCCAAAAATGAAGAAAGAGACAATTTTGTCTATAAATTCAAGTGCATCTCAGGTTGGGGTGAACAGGCCTATTGTTTGAGTGTCTTGGGAATTCCCCTATGTACACAAGTAAACTGTCAATCACGGAGGGTGCACAGCCAATGAGGTCGCAACAGGCAACCGATAATCAAGGACCAAATGGATAGACCTTTCATGGAGTATAGTTCATATTTCCTTATTGCTCCACTTTCTATAAATGACTTTAGACAGGAATCTATTGTTGGGTCTATGTGGAACGGAAAGATAAATATTAAAAGAAACGTAATTTTGCAATAATTAAATTTTTACACATTTGTACATAATTGTTTTTGTAAATCCCAAGTGCATTTAGAAAATTGCCAAATAATGAATTTGAGTTGTTTTTTTTTTTTTTAACAAAGGGAGATCTAAAATGAAATGTTATTATACGATTTTTTTTTTTATTGTGAATATGTAATATATTCTGTCGTTTTTGTAAATGGCGTGTGATGTTATACCTCATGTTGTCTTGTAAATATATTTTCACTGTCCAAGCAAAAAACATATTTAATTTTGTGTCTAAAAAAACCCCATGTAATAAACCAAAAAAAATCGAAAAAAAAAAAAAAA
Protein		Refseq >NP_989420\|hematopoietically-expressed homeobox protein hhex [Xenopus (Silurana) tropicalis] MQYQHPSSSALGLSVPLYAPTPLQPVHPTPFYIDDILGRSSASNGTPALPTPTLPSPNSSFTSLVATYRTPIYEPTPIHPAFTHPGAALAASYGASTYANPLYPFSRPVSEYTHALIRHDTLGKPLLWSPFIQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQGNKKDETESLENICEESQERCLSAEQKSRESSLDEPTSSPTSQETLDSEVSDDSDQEVDIEGDKGFYNCAH UniProtKB	Refseq >NP_001079059\|hematopoietically-expressed homeobox protein hhex [Xenopus laevis] MQYQHPSSSALGLSVPLFAPTPLQHPTPFYIDDILGRNSASNGTPALPTPTLPSPNSSFTSLVATYRTPIYEPTPIHPAFTHPGAALAASYGASTYASPLYPFSRPVSDYTHALIRHDSLGKPLLWSPFIQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQGNKKDETESLENICEESQERCLSAEQKSRESSLDDPTSSPTSQGNLDSEVSDDSDQEVDIEGDKGYYNCAH UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.111 [+] Str.70087	Xl.225 [+] Xl.63696 Xl.79603
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		115 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HHEX
mouse		MGI	Hhex	All(9) Targeted, knock Out(2) Targeted, other(4)
zebrafish		ZFIN	hhex	11 Lines(s)

Publications
First:		Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes. [Proc Natl Acad Sci U S A 1990]
Most recent:		Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. [Dev Biol 2013]
		View All Papers 24 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] Transcription factor HEX, contains HOX and HALZ domains

Reagents		tropicalis	laevis
Clones		EXRC - 2 clone(s)	EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.111.1.S1_at	Xl.225.1.S1_at
Affymetrix 2.0			Xl2.225.1.S2_at [+] Xl2.225.1.S1_at Xl2.22937.1.A1_at

Symbol legend[+]