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Summary Expression Gene Literature (259) GO Terms (48) Nucleotides (1084) Proteins (48) Interactants (1604) Wiki
XB-GENEPAGE-487199
Gene Symbol:
ctnnb1

Gene Name:
catenin beta 1

Synonyms:
beta-catenin , ctnnb1-b , ctnnb1-a , B-catenin , beta catenin , β-catenin ( Add synonyms , Nomenclature history )

Gene Function:
adherens junction protein/component of wnt signaling pathway

Protein Function :
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
medulloblastoma [+]

OMIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
GEO Series :
GSE93195.
1/7
 
Xenbase Gene ID XB-GENE-487200 XB-GENE-6254184 XB-GENE-487204
Gene Symbol ctnnb1 ctnnb1.L ctnnb1.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549712
399274
380441
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ctnnb1 ctnnb1.L ctnnb1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CTNNB1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ctnnb1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ctnnb1 Ensembl
zebrafish
ZFIN, AGR ctnnb1 ZFIN Ensembl
chicken
GEISHA CTNNB1 Ensembl
fruit fly
worm
Publications
First A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin., Science 1991  
Most Recent GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Cell Rep 2020                            
All View All Papers 43 paper(s) referencing morpholinos 10 paper(s) referencing OMIMs 18 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 24 terms 24 terms 10 terms
PANTHER ctnnb1
KEGG Pathways K02105 K02105 K02105
KOG [TZ] Armadillo/beta-Catenin/plakoglobin
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ctnnb1
Antibodies Ctnnb1 Ab2 , Ctnnb1 Ab3 , Ctnnb1 Ab1 , Ctnnb1 Ab4 , Ctnnb1 Ab5 , Ctnnb1 Ab6 , Ctnnb1 Ab7 , Ctnnb1 Ab8 , Ctnnb1 Ab9 , Ctnnb1 Ab10 , Ctnnb1 Ab11 , Ctnnb1 Ab12 , Ctnnb1 Ab 11 , Ctnnb1 Ab13 , Ctnnb1 AB16 Ctnnb1 Ab2 , Ctnnb1 Ab3 , Ctnnb1 Ab1 , Ctnnb1 Ab4 , Ctnnb1 Ab5 , Ctnnb1 Ab6 , Ctnnb1 Ab7 , Ctnnb1 Ab8 , Ctnnb1 Ab9 , Ctnnb1 Ab10 , Ctnnb1 Ab11 , Ctnnb1 Ab12 , Ctnnb1 Ab 11 , Ctnnb1 Ab13 , Ctnnb1 AB16 Ctnnb1 Ab2 , Ctnnb1 Ab3 , Ctnnb1 Ab1 , Ctnnb1 Ab4 , Ctnnb1 Ab5 , Ctnnb1 Ab6 , Ctnnb1 Ab7 , Ctnnb1 Ab8 , Ctnnb1 Ab9 , Ctnnb1 Ab10 , Ctnnb1 Ab11 , Ctnnb1 Ab12 , Ctnnb1 Ab 11 , Ctnnb1 Ab13 , Ctnnb1 AB16
Morpholinos ctnnb1 MO1 , ctnnb1 MO2 ctnnb1 MO1 , ctnnb1 MO2 ctnnb1 MO1 , ctnnb1 MO2
ORFs ctnnb1.L ORF1 , ctnnb1.L ORF2 ctnnb1.S ORF1 , ctnnb1.S ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

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