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Summary Expression Gene Literature (60) GO Terms (33) Nucleotides (151) Proteins (39) Interactants (870) Wiki
XB-GENEPAGE-487308
Gene Symbol:
gdf3

Gene Name:
growth differentiation factor 3

Synonyms:
derrière , derriere , vgr2 , vgr-2 , gdf-3 ( Add synonyms , Nomenclature history )

Gene Function:
tgf-beta related peptide growth factor

Protein Function :
Required for posterior mesoderm formation during embryogenesis. Acts indirectly to suppress head formation by altering mesodermal patterning. Also involved in the establishment of left-right axis asymm...[+]


InterPro :
TGF-b propeptide , TGF-beta-rel , Cystine-knot cytokine , TGF-b C [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
isolated microphthalmia 7 [+]

OMIM:
KLIPPEL-FEIL SYNDROME 3, AUTOSOMAL DOMINANT; KFS3 [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-487309 XB-GENE-17343554 XB-GENE-865693
Gene Symbol gdf3 gdf3.L gdf3.S
Chromosome Chr1 Scaffold21
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 493288
394305
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gdf3 gdf3.L gdf3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GDF3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gdf3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gdf3 Ensembl
zebrafish
ZFIN, AGR gdf3 ZFIN Ensembl
chicken
GEISHA GDF3 Ensembl
fruit fly
worm
Publications
First Identification and cloning of localized maternal RNAs from Xenopus eggs., Cell 1985  
Most Recent Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Elife 2020                        
All View All Papers 11 paper(s) referencing morpholinos 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 0 term 16 terms
PANTHER gdf3
KEGG Pathways K05495 [+] K05495 [+]
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gdf3
Antibodies Gdf3 Ab1 Gdf3 Ab1
Morpholinos (on-target & off-target) gdf3 MO1
ORFs gdf3 ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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