Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (728) GO Terms (31) Nucleotides (140) Proteins (45) Interactants (1282) Wiki
XB-GENEPAGE-487457
Gene Symbol:
gata4

Gene Name:
GATA binding protein 4

Synonyms:
xGATA-4 , gata-4 , xgata4 , gata4-a , gata4-b ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger transcription factor

Protein Function :
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3'. Associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Activates the ex...[+]


InterPro :
Transcription factor GATA , Znf GATA , TF GATA 4/5/6 , Znf NHR/GATA [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
familial atrial fibrillation [+]

OMIM:
TETRALOGY OF FALLOT; TOF [+]

External Links:
1/7
 
Xenbase Gene ID XB-GENE-487458 XB-GENE-487462 XB-GENE-6256576
Gene Symbol gata4 gata4.L gata4.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549703
443781
399302
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gata4 gata4.L gata4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GATA4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gata4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gata4 Ensembl
zebrafish
ZFIN, AGR gata4 ZFIN Ensembl
chicken
GEISHA GATA4 Ensembl
fruit fly
worm
Publications
First GATA-4 is a novel transcription factor expressed in endocardium of the developing heart., Development 1993                  
Most Recent Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis., Genes (Basel) 2020                    
All View All Papers 25 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 6 terms 11 terms
PANTHER gata4
KEGG Pathways K09183 K09183 K09183
KOG [K] GATA-4/5/6 transcription factors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gata4
Morpholinos gata4 MO1 , gata4 MO2 , gata4 MO3 , gata4 MO4 gata4 MO1 , gata4 MO2 , gata4 MO3 , gata4 MO4 gata4 MO1 , gata4 MO2 , gata4 MO3 , gata4 MO4
ORFs gata4.L ORF1 gata4.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list