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Summary Expression Gene Literature (27) GO Terms (1) Nucleotides (50) Proteins (22) Interactants (229) Wiki
XB-GENEPAGE- 487810

Gene Symbol: nphs1

Gene Name: NPHS1 nephrin

Synonyms: nephrin
Add Xenopus synonyms , Nomenclature history


Gene Function: transmembrane protein, component of slit diaphragm, cell signaling

Protein Function:


Interactants: Loading ...

OMIM Disease Associations: NEPHROTIC SYNDROME, TYPE 1; NPHS1
1/5
 
Xenbase Gene ID XB-GENE-487811 XB-GENE-17335666 XB-GENE-487815
Gene Symbol nphs1 nphs1.L nphs1.S
Chromosome scaffold_37 chr7S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.14805
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 39 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine nphs1 nphs1.L nphs1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NPHS1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Nphs1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN nphs1 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First: Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers. [J Biol Chem 2003]
Most recent: pdzrn3 is required for pronephros morphogenesis in Xenopus laevis. [Int J Dev Biol 2016]
View All Papers 12 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 1 terms
EC protein-tyrosine-phosphatase
PANTHER nphs1
KEGG Pathways
KOG [R] Predicted transmembrane protein of the immunoglobulin family of cell adhesion molecules
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Affymetrix 1.0 StrEns.8351.1.S1_at
Affymetrix 2.0 Xl2.14805.1.S1_at

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