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Summary Expression Gene Literature (91) GO Terms (26) Nucleotides (209) Proteins (49) Interactants (325) Wiki
XB-GENEPAGE-488469
Gene Symbol:
tbp

Gene Name:
TATA-box binding protein

Synonyms:
xtbp , gtf2d , sca17 , tfiid , gtf2d1 , tbp-a , tbp-b ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional regulator

Protein Function :
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex ...[+]


InterPro :
MAP2/MAP4/Tau , MAP tubulin-bd rpt , TBP dom sf , TBP CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
spinocerebellar ataxia type 17 [+]

OMIM:
PARKINSON DISEASE, LATE-ONSET; PD [+]

External Links:
GEO Series :
GSE76994.
 
Xenbase Gene ID XB-GENE-488470 XB-GENE-6253887 XB-GENE-865786
Gene Symbol tbp tbp.L tbp.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549093
399465
503680
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tbp tbp.L tbp.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TBP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tbp MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tbp Ensembl
zebrafish
ZFIN, AGR tbp ZFIN Ensembl
chicken
GEISHA TBP Ensembl
fruit fly
FLYBASE Tbp Ensembl
worm
Publications
First Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II., Cell 1987  
Most Recent Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2., Nat Commun 2019                                    
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 8 terms 4 terms
PANTHER tbp
KEGG Pathways K03120 K03120 K03120
KOG [K] TATA-box binding protein (TBP), component of TFIID and TFIIIB
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tbp
Antibodies Tbp Ab1 , Tbp Ab2 Tbp Ab1 , Tbp Ab2 Tbp Ab1 , Tbp Ab2
Morpholinos (on-target & off-target) tbp MO1 tbp MO1 tbp MO1
ORFs tbp.L ORF1 tbp.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info