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Summary Expression Gene Literature (14) GO Terms (10) Nucleotides (405) Proteins (52) Interactants (182) Wiki
XB-GENEPAGE-488501
Gene Symbol:
mdk

Gene Name:
midkine

Synonyms:
midkine , negf2 , PTF-alpha-1 , PTF-alpha-2 , mdk-b , mdk-a , ptf-b , ptf-beta , ptf-a , ptf-alpha ( Add synonyms , Nomenclature history )

Gene Function:
growth factor

Protein Function :
Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via the...[+]


InterPro :
PTN/MK diS sf , PTN/MK N dom sf , Midkine heparin-bd GF , PTN MK heparin-bd GF CS [+]

Interactants:
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Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-488502 XB-GENE-6254190 XB-GENE-488506
Gene Symbol mdk mdk.L mdk.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394671
399256
397791
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine mdk mdk.L mdk.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MDK OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mdk MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mdk Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR mdkb mdka ZFIN Ensembl
chicken
GEISHA MDK Ensembl
fruit fly
worm
Publications
First Cloning and sequence of the Xenopus laevis homologue of the midkine cDNA., Gene 1994  
Most Recent Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos., Sci Rep 2020                        
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 9 terms 9 terms
PANTHER mdk
KEGG Pathways K06828 K06828 K06828
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks mdk
ORFs mdk ORF1 mdk.L ORF1 mdk.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info