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Summary Expression Gene Literature (21) GO Terms (7) Nucleotides (175) Proteins (44) Interactants (103) Wiki
XB-GENEPAGE-489954
Gene Symbol:
rangap1

Gene Name:
Ran GTPase activating protein 1

Synonyms:
fug1 , rna1p , rangap1-a , rangap1-b ( Add synonyms , Nomenclature history )

Gene Function:
GTPase activator

Protein Function :
GTPase activator for RAN, converting it to the GDP-bound state (PubMed:9108047). Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is required for RAN-mediated nuclear import and export.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-489955 XB-GENE-489959 XB-GENE-6464329
Gene Symbol rangap1 rangap1.L rangap1.S
Chromosome Chr04 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100144714
379922
100337588
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rangap1 rangap1.L rangap1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards RANGAP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rangap1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rangap1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR rangap1b rangap1a ZFIN Ensembl
chicken
GEISHA RANGAP1 Ensembl
fruit fly
worm
Publications
First Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1., Biochemistry 1995  
Most Recent RanBP1 governs spindle assembly by defining mitotic Ran-GTP production., Dev Cell 2014  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 2 terms 2 terms 7 terms
PANTHER rangap1
KEGG Pathways K14319 K14319 K14319
KOG [AYT] Ran GTPase-activating protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rangap1
ORFs rangap1.L ORF1 rangap1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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