Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (127) GO Terms (20) Nucleotides (77) Proteins (40) Interactants (311) Wiki
XB-GENEPAGE-490074
Gene Symbol:
lhx3

Gene Name:
LIM homeobox 3

Synonyms:
LIM-3 , xLIM-3 , lim3 ( Add synonyms , Nomenclature history )

Gene Function:
LIM and homeodomain containing transcription factor

Protein Function :
May be involved in the specification and maintenance of differentiation of distinct neuronal and neuroendocrine tissues. Early marker for the pituitary and pineal lineages, it may be involved in specif...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypopituitarism

OMIM:
PITUITARY HORMONE DEFICIENCY, COMBINED, 2; CPHD2 [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-490075 XB-GENE-865930 XB-GENE-17344008
Gene Symbol lhx3 lhx3.L lhx3.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100489308
397959
108699903
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lhx3 lhx3.L lhx3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LHX3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lhx3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lhx3 Ensembl
zebrafish
ZFIN, AGR lhx3 ZFIN Ensembl
chicken
GEISHA LHX3 Ensembl
fruit fly
worm
Publications
First Expression of LIM class homeobox gene Xlim-3 in Xenopus development is limited to neural and neuroendocrine tissues., Dev Biol 1993                
Most Recent Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Dev Biol 2017                            
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 7 terms 6 terms
PANTHER lhx3
KEGG Pathways K09374 K09374
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lhx3
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list