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Summary Expression Gene Literature (31) GO Terms (23) Nucleotides (42) Proteins (25) Interactants (93) Wiki
XB-GENEPAGE-490480
Gene Symbol:
gja5

Gene Name:
gap junction protein alpha 5

Synonyms:
connexin 40 , cx40 , connexin40 ( Add synonyms , Nomenclature history )

Gene Function:
connexon channel component

Protein Function :
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.



Interactants:
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Diseases: 


Disease Ontology:
familial atrial fibrillation [+]

OMIM:
ATRIAL STANDSTILL 1; ATRST1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-490481 XB-GENE-17341723 XB-GENE-17341724
Gene Symbol gja5 gja5.L gja5.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100489536
108707841
108709260
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein TrEMBL NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gja5 gja5.L gja5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GJA5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gja5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gja5 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR gja5b gja5a ZFIN Ensembl
chicken
GEISHA GJA5 Ensembl
fruit fly
worm
Publications
First Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung., J Cell Biol 1992  
Most Recent Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice., Hypertension 2015  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 3 terms 3 terms
PANTHER gja5
KEGG Pathways K07614 K07614 K07614
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gja5
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

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