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Summary Expression Gene Literature (14) GO Terms (26) Nucleotides (407) Proteins (51) Interactants (231) Wiki
XB-GENEPAGE-491383
Gene Symbol:
lin28a

Gene Name:
lin-28 homolog A

Synonyms:
lin-28 , csdd1 , zcchc1 , lin28 ( Add synonyms , Nomenclature history )

Gene Function:
RNA-binding protein invovled in translation or RNA processing

Protein Function :
RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism. Seems to recognize a common structura...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-491384 XB-GENE-17334846 XB-GENE-866059
Gene Symbol lin28a lin28a.L lin28a.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548523
108708102
387262
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine lin28a lin28a.L lin28a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LIN28A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lin28a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lin28a Ensembl
zebrafish
ZFIN, AGR lin28a ZFIN Ensembl
chicken
GEISHA LIN28A Ensembl
fruit fly
worm
Publications
First Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites., Dev Biol 2003          
Most Recent Overexpression of Lin28a delays Xenopus metamorphosis and down-regulates albumin independently of its translational regulation domain., Dev Dyn 2019            
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 26 terms 2 terms 18 terms
PANTHER lin28a
KEGG Pathways K18754 K18754 K18754
KOG [J] Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks lin28a
Antibodies Lin28a Ab1 Lin28a Ab1
Morpholinos lin28a MO1 , lin28a MO2 lin28a MO1 , lin28a MO2 lin28a MO1 , lin28a MO2
ORFs lin28a ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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