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Summary Expression Gene Literature (10) GO Terms (8) Nucleotides (112) Proteins (38) Interactants (111) Wiki
XB-GENEPAGE-492105
Gene Symbol:
nefl

Gene Name:
neurofilament, light

Synonyms:
XNF-L , NF-L ( Add synonyms , Nomenclature history )

Gene Function:
intermediate filament

Protein Function :
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with other neuronal inter...[+]



Interactants:
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Diseases: 


Disease Ontology:
Charcot-Marie-Tooth disease type 1F [+]

OMIM:
CHARCOT-MARIE-TOOTH DISEASE, DEMYELINATING, TYPE 1F; CMT1F [+]

External Links:
 
Xenbase Gene ID XB-GENE-492106 XB-GENE-866125 XB-GENE-17335528
Gene Symbol nefl nefl.L nefl.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100216135
397822
108712714
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine nefl nefl.L nefl.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NEFL OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nefl MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nefl Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR neflb nefla ZFIN Ensembl
chicken
GEISHA NEFL Ensembl
fruit fly
worm
Publications
First Identities, antigenic determinants, and topographic distributions of neurofilament proteins in the nervous systems of adult frogs and tadpoles of Xenopus laevis., J Comp Neurol 1988  
Most Recent Developmental gene expression patterns in the brain and liver of Xenopus tropicalis during metamorphosis climax., Genes Cells 2018                
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 3 terms 3 terms
PANTHER nefl
KEGG Pathways K04572 K04572 K04572
KOG [DY] Nuclear envelope protein lamin, intermediate filament superfamily
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks nefl
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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