cirbp Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (10)

Nucleotides (14247)

Interactants (28)

XB-GENEPAGE-492780

Gene Symbol: cirbp Gene Name: cold inducible RNA binding protein Synonyms: Xcirp, cirp, cirbp-a, cirp1, cirbp-b, cirbp2 Add Xenopus synonyms Gene Function: cytoplasmic RNA-binding protein Interactants: lef1(2) , tcf3(2) , tcf4(2) , tcf7(2) , tcf7l1(2) , tcf7l2(2) , tle4(2) View All

XB-GENE-492781

XB-GENE-6256647

XB-GENE-492785

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001017228\|Xenopus (Silurana) tropicalis cold inducible RNA binding protein (cirbp), mRNA GCGCACTTCGCATTCGGCTTCCAACTTGTGTTGTATCGTCCGAAGATCATAGAACGTCTCACCATGTCTTGTGATGAAGGAAAACTCTTTGTCGGTGGTCTGAATTTTGAAACCACAGAGGAAAGCTTGGAGCAAGTGTTTAGCAAATATGGACAGGTTGCTGAAGTGGTTGTGGTGAAGGATCGGGAAAGCAAGAGATCCAGAGGCTTTGGCTTTGTCACATTTGAGAATCCTGAAGATGCCAAGGATGCTATGATGGCAATGAATGGGAAGTCTGTAGATGGCCGTCAAATCCGTGTTGATCAGGCTGGCAAGTCCTCCAATGATAGGAGAGGTGGTTACAGAGGTGGCTCTTCTGGAGGCAGAGGGTTCTTCCGTGGAGGCAGAGGCCGAGGTGGTGGTGGAGACAGAGGATATGGTGGAAGCAGCCGCTTTGAAAACAGAAGTGGAGGTTACCAAAGCAGTGGATCCAGGGATTACTATGGCAGGAGTCATGGAAGCTATGGTGATCGTTCCGGAGGATCCTACAGGGATAGTTATGACAGCTATACTACACAAGAGTAAAATCCATTCCTGACTCAAGATCGTCCTTCCAATGGCTGTATTTATAAAGATTTTTGGAGCTTCGCCGAATCGTTTGTGTAGTATATCTACTTGTGTTCACTTTTTTTTTTAATAGACCTAGTTAGCCTGACAGCTTCTCTAATAAGTGGGACAGCTGTGTTTCAAAGGCTTTATCTTTGGACACCTAATCTCATTCTTAAAGTTACTGTGTTCTGCAAGGATATTCCTATCCTACTATGCTGTTCCATTCAAGCTGATCAGGTGGGGCTGCTCCCCCTTCTGGTTAAGTAGTGCTAGGAAGTAACTTCCTAAGCGGATGGGTGCTGTTGGTTGATGGGCAGAGAAGCACCTGTATTAGTAGCAGACTGCTAGGCCTGTCTTCCTGTAGCATTGTTTAAAGAACTTTAAGCTGCTGTATTTTTTGGTTACATGAAAAGTTAATTTTATGAGTCCACTTAAATTGCATTCCTTTAGTGTAACAAGGCAAGGCAGAGCTTGGGTGCGCTGTATATAGTGGCTACACCTCCTTGATACACAAAGTGAATAGTGTTCGCATCTCCAGTAACAATATCAGAAGAAGTTCTTAAAATGTTTGTTTATATTGTCCTTTTTTTACTAAACATGCAACTATTGTACTGAAGTGGCTAAGGAATTGTATTCTACTTTTGATTGGCTTCACGAAGCCTATTAAAAAAACCAATGTGAAAAGAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001086600\|Xenopus laevis cold inducible RNA binding protein (cirbp-a), mRNA TTCTAAGCGGTGTTCATTTGTTTGACGAGCAGCAAACGTTCCATCATGTCTGACGAAGGAAAACTCTTTATTGGTGGTCTGAATTTTGAAACCAATGAGGACTGCTTGGAGCAAGCATTTACCAAATATGGACGGATTTCTGAAGTGGTTGTGGTGAAAGATCGGGAAACCAAGAGATCAAGAGGCTTTGGCTTTGTTACATTTGAGAATGTTGATGATGCCAAGGATGCTATGATGGCAATGAATGGAAAGTCTGTGGACGGTCGTCAAATCCGCGTTGATCAGGCTGGCAAGTCATCTGGGGAAAGGCGAGGTGGTTACAGAGGTGGCTCTTCTGGAGGCAGAGGCTTCTTCCGTGGAGGCAGGGGCCGAGGTGGTGGAGACAGAGGATATGGAAGCAGCCGTTTTGACAACAGAAGTGGCGGTTATGGTGGTAGCAGTGGATCCAGGGATTACTATGGCAGTGGCAGGAGTCAAGGCAGTTATGGTGATCGTTCTGGAGGTTCCTACAGGGATAGTTACGACAGCTATGCTACACACGAGTAAAATCCATTCCTGACTCAAGATCGTCCTTCCAATGGCTGTATTTATAAAGATTTTTGGAGCTTCGCCGAATCGTTCGTGTAGTATATCTACTTGTGTTCAATTTTTTTTTTTTTTTAATTGACCTAGTTTGCCTGACAGCTTCTCTAATTTGTGGGACAGCTGTGTCTCAAAAGCTTTAGCTTTGGACACCTAATCTCATTAAAGTTACTGTGTTCTGCAGGGATATTGCTATCCTACTATGCTGTTCCATTTGGGCTGATCAGGCGGGGCCACCCCCCTTCTTCTGTTTAAGTAGTGCTGGGAAGTGGATGGGTGCTGATGGGCAGAGAAGCACCTGTTAGTAGACTGCTAGGCCTGTCCTCCTGTAGCATTGTCTCTGAACTTTAAGCTGCTGTATTTTTGGGTTACATGAAAAGTTTAATTTTATGAGTCCACTTAAAATTGCATTCCTTTAGTGTAACAAGGCAGGACAGAGCCTGGGTGCGCTGTACATAGTGGCTACACCTCCTTGATACACAAAGTGAATTAGTGTTCATATCTCCAGTAAACAATGTCAGAAGTTCTTAAAATGTTTGTTTATATTGTCCTTTTCTTTTTTTACTAAAACATGCAACTATTGTACTGAAGTGGCTAAGGAATTGTATTCTACTTTTGATTGGCTTCACGAAGCCTATTAAAAAAACAATGAAAAGAAAAAAAAAAAAAAAA		Refseq >NM_001086325\|Xenopus laevis cold inducible RNA binding protein (cirbp-b), mRNA GCACTTCGCATTCGGCTTCTAAGTGGTGTTGACTTGTTTGAAGATCAATAAACGTCTCGTCATGTCTGATGAAGGAAAACTCTTTATCGGTGGTCTGAATTTTGACACCAATGAGGAAAGCTTGGAGCAAGTGTTTAGCAAATATGGGCAGATCTCTGAAGTTGTTGTGGTGAAGGATCGGGAAACAAAGAGATCAAGAGGATTTGGCTTTGTCACATTTGAGAATCCTGATGATGCCAAGGATGCTATGATGGCAATGAATGGGAAGGCTGTAGATGGCCGTCAAATCCGCGTTGATCAGGCTGGCAAGTCTTCTGGTGATAGAAGAGGTGGTTACAGAGGTGGCTCTTCTGGAGGCAGAGGCTTCTTCCGTGGAGGCAGAGGCCGAGGTGGTGGAGACAGAGGATATGGAAGCAGCCGTTTTGATAACAGAAGTGGAGGTTATGGCGGTAGCAGTGGATCCAGGGACTATTATAGCAGTGGCAGGAGTCAAGGCAGCTATGGTGATCGTGCTGGAGGTTCCTACAGAGATAGCTACGACAGTTATGCTACACACGAGTAAAATCCATTCCTGACTCAAGATCGTCCTTCCAATGGCTGTATTTATAAAGATTTTTGGAGCTTCGCCGAATCGTTTGTGTAGTATATCTACTTGTGTTCACTTTTTTTTTTTTTAATAGACAGTTAGCCTGACAGCTTCTCTAATTTGTTGGACAGCTGTGTATCAAAGACTTTAATCTTTGGACACCTAATCTCATTCTTAAAGTTAATGTGTTCTGCAGGGATATTCCTATCCTACTATGCTGTTCCATTCAGGCTGATCAGGTGGGATTGCTTGCCTTTCTGGTCAAGTAGTGCTGGGAAGTAACTTCCTAAGCGGATAGGTGCTGTTAGGAGAGAAACAGAGAACCACCTGTGTTAGTAGCAGACTGCTAGGAGCACCTATGATGATAATAGCAGACTGTTAGGCTTGTCCTGTAGCATTTTCTCAAGAACTTTAAGCTGCTGTATTTTTGGGTTACATGAAGTTAATTTTATGTGAAGTCCACTTAAAATTTCAATCCTTTAGTGTAACAAGGCAGGGCAGAGCCTGGGTGCGCTGTATATAGTGGCTACACCTCCTTGATACATAAAGTGAATAGTGTTCGTCTCTCTCCAGTAAAATGTCAGAAGTTCTTAAAATGTTTGTTTATATTGTCAGTTTTTTTTTTTACTAAAACATGCAACTATTGTACTGAAGTGGCAAAGGAATTGTATTCTACTTTCGATTGGCTTCACGAAGCCTATTAAAAAACCAATGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001017228\|cold-inducible RNA-binding protein [Xenopus (Silurana) tropicalis] MSCDEGKLFVGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMMAMNGKSVDGRQIRVDQAGKSSNDRRGGYRGGSSGGRGFFRGGRGRGGGGDRGYGGSSRFENRSGGYQSSGSRDYYGRSHGSYGDRSGGSYRDSYDSYTTQE UniProtKB	Refseq >NP_001080069\|cold-inducible RNA-binding protein A [Xenopus laevis] MSDEGKLFIGGLNFETNEDCLEQAFTKYGRISEVVVVKDRETKRSRGFGFVTFENVDDAKDAMMAMNGKSVDGRQIRVDQAGKSSGERRGGYRGGSSGGRGFFRGGRGRGGGDRGYGSSRFDNRSGGYGGSSGSRDYYGSGRSQGSYGDRSGGSYRDSYDSYATHE UniProtKB		Refseq >NP_001079794\|cold-inducible RNA-binding protein B [Xenopus laevis] MSDEGKLFIGGLNFDTNEESLEQVFSKYGQISEVVVVKDRETKRSRGFGFVTFENPDDAKDAMMAMNGKAVDGRQIRVDQAGKSSGDRRGGYRGGSSGGRGFFRGGRGRGGGDRGYGSSRFDNRSGGYGGSSGSRDYYSSGRSQGSYGDRAGGSYRDSYDSYATHE UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.47654 [+] Str.35779 Str.11564 Str.28145 Str.37031 Str.43930 Str.45184 Str.45760 Str.45811 Str.46293 Str.46935 Str.48351 Str.58654 Str.61418 Str.21776	Xl.4515		Xl.8151 [+] Xl.84061 Xl.2299 Xl.9689
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		6 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CIRBP
mouse		MGI	Cirbp	All(2) Targeted, knock Out(1)
zebrafish		ZFIN	cirbp

Publications
First:		XCIRP (Xenopus homolog of cold-inducible RNA-binding protein) is expressed transiently in developing pronephros and neural tissue. [Gene 1998]
Most recent:		Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors. [Dev Biol 2012]
		View All Papers 3 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		nucleic acid binding
Biological:
Cellular Component:
EC:
KOG:		[A] Alternative splicing factor SRp20/9G8 (RRM superfamily)

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.8239.1.S1_x_at [+] Str.8239.1.S1_at Str.21776.1.A1_at Str.50718.1.A1_at Str.32470.1.A1_at Str.35779.1.A1_s_at Str.35779.1.A1_x_at Str.35704.1.A1_at Str.35956.1.A1_x_at Str.35956.1.A1_at Str.17177.1.A1_at Str.31527.2.A1_at Str.43817.1.A1_at Str.43817.1.A1_x_at Str.43817.2.A1_x_at Str.43930.1.A1_at Str.28145.1.S1_at Str.44133.1.A1_a_at Str.44133.1.A1_at Str.44140.1.A1_at Str.44579.1.A1_at Str.19183.1.A1_at Str.41034.1.S1_at Str.45184.1.A1_x_at Str.45184.1.A1_s_at Str.45466.1.A1_at Str.47086.1.S1_at Str.48351.1.A1_x_at Str.45760.1.A1_at Str.45811.1.A1_at Str.46293.1.A1_at Str.44936.1.A1_a_at Str.46935.1.A1_at Str.11158.1.A1_at Str.11593.1.A1_x_at Str.4907.1.A1_at	Xl.4515.1.S2_a_at [+] Xl.4515.1.S1_at		Xl.9689.2.A1_at
Affymetrix 2.0			Xl2.4515.1.S1_at		Xl2.8151.1.S1_x_at [+] Xl2.8151.3.S1_x_at Xl2.56962.1.A1_s_at Xl2.8151.2.S1_x_at Xl2.8151.2.S1_at Xl2.9689.3.A1_at Xl2.9689.1.A1_at

Symbol legend[+]