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Summary Expression Gene Literature (53) GO Terms (5) Nucleotides (49) Proteins (28) Interactants (149) Wiki
XB-GENEPAGE-493229
Gene Symbol:
gja8

Gene Name:
gap junction protein alpha 8

Synonyms:
connexin 50 , cx50 , alpha8 connexin , connexin50 , mp70 ( Add synonyms , Nomenclature history )

Gene Function:
connexon channel component

Protein Function :
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
chromosome 1q21.1 deletion syndrome [+]

OMIM:
CATARACT 1, MULTIPLE TYPES; CTRCT1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-493230 XB-GENE-17344922 XB-GENE-866236
Gene Symbol gja8 gja8.L gja8.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100490617
108707839
100381091
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine gja8 gja8.L gja8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GJA8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gja8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gja8 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR gja8b gja8a ZFIN Ensembl
chicken
GEISHA GJA8 Ensembl
fruit fly
worm
Publications
First Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes., J Cell Biol 1991  
Most Recent Modeling ocular lens disease in Xenopus., Dev Dyn 2020            
All View All Papers 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 0 term 0 term
PANTHER gja8
KEGG Pathways
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks gja8
Clones Horizon Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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