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Summary Expression Gene Literature (13) GO Terms (8) Nucleotides (165) Proteins (31) Interactants (184) Wiki
XB-GENEPAGE-493952
Gene Symbol: itga5

Gene Name: integrin subunit alpha 5

Synonyms: VLA-5 , Integrin alpha5 ( Add synonyms , Nomenclature history )

Gene Function: cell surface receptor subunit

Protein Function :
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent ...[+]

Interactants: Loading ...
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Xenbase Gene ID XB-GENE-493953 XB-GENE-866304 XB-GENE-17340799
Gene Symbol itga5 itga5.L itga5.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine itga5 itga5.L itga5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ITGA5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Itga5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR itga5 ZFIN Ensembl
chicken
GEISHA ITGA5 Ensembl
fruit fly
worm
WORMBASE
Publications
First Fibronectin-rich fibrillar extracellular matrix controls cell migration during amphibian gastrulation., Int J Dev Biol 1990                
Most Recent ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis., Sci Transl Med 2018    
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 7 terms 3 terms
PANTHER itga5
KEGG Pathways K06484 K06484
KOG [W] Vitronectin receptor, alpha subunit
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Itgb1 Ab3 , Itgb1 Ab4 , Itga5 Ab1 Itgb1 Ab3 , Itgb1 Ab4 , Itga5 Ab1
Morpholino itga5 MO1 itga5 MO1 itga5 MO1
Affymetrix 1.0 Str.3950.1.S1_at [+] Xl.1049.1.S1_s_at [+]
Affymetrix 2.0 Xl2.1049.1.S1_s_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.0


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