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Summary Expression Gene Literature (2) GO Terms (11) Nucleotides (79) Proteins (36) Interactants (456) Wiki
XB-GENEPAGE-493996
Gene Symbol:
vhl

Gene Name:
von Hippel-Lindau tumor suppressor

Synonyms:
vhl1 ( Add synonyms , Nomenclature history )

Gene Function:
E3 ubiquitin ligase

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
nonpapillary renal cell carcinoma [+]

OMIM:
PHEOCHROMOCYTOMA [+]

External Links:
 
Xenbase Gene ID XB-GENE-493997 XB-GENE-17344358 XB-GENE-6487931
Gene Symbol vhl vhl.L vhl.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549121
108714636
108715855
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine vhl vhl.L vhl.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tegg131f10      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards VHL OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Vhl MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Vhl Ensembl
zebrafish
ZFIN, AGR vhl ZFIN Ensembl
chicken
GEISHA VHL Ensembl
fruit fly
FLYBASE Vhl Ensembl
worm
Publications
First Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., PLoS Genet 2006                                      
Most Recent Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Nat Cell Biol 2008          
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 0 term 0 term
PANTHER vhl
KEGG Pathways K03871 K03871
KOG [O] E3 ubiquitin ligase, VHL component (von Hippel-Lindau tumor suppressor in humans)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks vhl
Morpholinos vhl MO1 vhl MO1 vhl MO1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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