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Summary Expression Gene Literature (1261) GO Terms (0) Nucleotides (78) Proteins (17) Interactants (803) Wiki
XB-GENEPAGE-5719326
Gene Symbol:
h2ac21

Gene Name:
H2A clustered histone 21

Synonyms:
h2a , XH2AX , H2AX , hist2h2ab ( Add synonyms , Nomenclature history )

Gene Function:
Histone 2A

Protein Function :
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5719327 XB-GENE-22066267 XB-GENE-22066269
Gene Symbol h2ac21 h2ac21.L h2ac21.S
Chromosome Chr9
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0
CDS Gene model
Entrez Gene 594911
mRNA RefSeq
Protein NCBI Protein RefSeq
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine h2ac21 h2ac21.L h2ac21.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards H2AC21 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR H2ac21 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR H2ac21 Ensembl
zebrafish
chicken
fruit fly
worm
Publications
First Reiteration frequency of the histone genes in the genome of the amphibian, Xenopus laevis., Eur J Biochem 1976  
Most Recent Structure of a single-chain H2A/H2B dimer., Acta Crystallogr F Struct Biol Commun 2020  
All View All Papers 2 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 0 term 0 term
PANTHER h2ac21
KEGG Pathways
KOG [B] Histone 2A
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks h2ac21
Morpholinos hist2h2ab MO1 hist2h2ab MO1 hist2h2ab MO1
Clones Horizon Source BioScience
Plasmids Addgene Addgene

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