Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (4) GO Terms (6) Nucleotides (177) Proteins (38) Interactants (514) Wiki
XB-GENEPAGE-5745093
Gene Symbol: ric8a

Gene Name: RIC8 guanine nucleotide exchange factor A

Synonyms: synembryn , ric-8 , xtric-8 , ric-8A , ric8a-a , ric8a-b ( Add synonyms , Nomenclature history )

Gene Function: regulates neurotransmitter secretion

Protein Function :
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitoti...[+]

Interactants: Loading ...
1/6
 
Xenbase Gene ID XB-GENE-5745094 XB-GENE-6464316 XB-GENE-5745170
Gene Symbol ric8a ric8a.L ric8a.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ric8a ric8a.L ric8a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards RIC8A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ric8a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ric8a ZFIN Ensembl
chicken
GEISHA RIC8A Ensembl
fruit fly
FLYBASE ric8a Ensembl
worm
WORMBASE
Publications
First Cloning and spatiotemporal expression of RIC-8 in Xenopus embryogenesis., Gene Expr Patterns 2011            
Most Recent The Ric-8A/Gα13/FAK signalling cascade controls focal adhesion formation during neural crest cell migration in Xenopus., Development 2018                                
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 0 term
PANTHER ric8a
KEGG Pathways
KOG [T] Signaling protein RIC-8/synembryn (regulates neurotransmitter secretion)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody ric8a Ab1 ric8a Ab1 ric8a Ab1
Morpholino ric8a MO1 ric8a MO1 ric8a MO1
ORF ric8a.S ORF1
Affymetrix 1.0 Str.8566.1.S1_at [+] Xl.22237.1.S1_at [+]
Affymetrix 2.0 Xl2.22237.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.0


Major funding for Xenbase is provided by grant P41 HD064556