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Summary Expression Gene Literature (55) GO Terms (6) Nucleotides (88) Proteins (34) Interactants (222) Wiki
XB-GENEPAGE-5762129
Gene Symbol:
apcdd1

Gene Name:
adenomatosis polyposis coli down-regulated 1

Synonyms:
drapc1 , xPgo ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypotrichosis 1

OMIM:
HYPOTRICHOSIS 1; HYPT1

External Links:
 
Xenbase Gene ID XB-GENE-5762130 XB-GENE-5762142 XB-GENE-17340935
Gene Symbol apcdd1 apcdd1.L apcdd1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448576
447402
108695251
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine apcdd1 apcdd1.L apcdd1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards APCDD1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Apcdd1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Apcdd1 Ensembl
zebrafish
chicken
GEISHA APCDD1 Ensembl
fruit fly
worm
Publications
First APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex., Nature 2010        
Most Recent Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin., Dev Biol 2020  
All View All Papers 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 6 terms 0 term
PANTHER apcdd1
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks apcdd1
ORFs apcdd1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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