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Summary Expression Gene Literature (5) GO Terms (15) Nucleotides (211) Proteins (29) Interactants (236) Wiki
XB-GENEPAGE-5816926
Gene Symbol:
kdm1a

Gene Name:
lysine (K)-specific demethylase 1A

Synonyms:
lsd1 , aof2 , xLSD1 , kdm1 ( Add synonyms , Nomenclature history )

Gene Function:
oxidoreductase

Protein Function :
Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substra...[+]



Interactants:
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Diseases: 


OMIM:
CLEFT PALATE, PSYCHOMOTOR RETARDATION, AND DISTINCTIVE FACIAL FEATURES; CPRF

External Links:
1/2
 
Xenbase Gene ID XB-GENE-5816927 XB-GENE-17336821 XB-GENE-5816963
Gene Symbol kdm1a kdm1a.L kdm1a.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100216250
108708259
100127344
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine kdm1a kdm1a.L kdm1a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KDM1A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kdm1a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kdm1a Ensembl
zebrafish
ZFIN, AGR kdm1a ZFIN Ensembl
chicken
GEISHA KDM1A Ensembl
fruit fly
worm
Publications
First Characterization of histone lysine-specific demethylase in relation to thyroid hormone-regulated anuran metamorphosis., Dev Growth Differ 2007            
Most Recent A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex., Cell Rep 2019  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 6 terms 0 term
PANTHER kdm1a
KEGG Pathways K11450
KOG [Q] Amine oxidase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks kdm1a
Antibodies Kdm1a Ab1 Kdm1a Ab1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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