[provisional- machine annotated only] Gene Symbol: pgc [Predicted: Source is Human Entrez Gene] Gene Name: progastricsin (pepsinogen C) [Predicted: Source is Human Entrez Gene] Add Xenopus synonyms Gene Function: aspartyl protease Interactants: pgat(11) , ddx4(8) , ddx25(6) , dnd1(6) , dazl(5) , cxcr4(3) , cyp26a1(3) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1
		Entrez Gene
mRNA		Refseq >NM_001015682|Xenopus (Silurana) tropicalis progastricsin (pepsinogen C) (pgc), mRNA TGCATTACTTGATTCCTGCACAATGAAGTGGATCATTTTTACTTTTTTTTGTCTCTATCTTTCAGAGGGGCTGGTAAGAGTTCCATTGAAAAGATTCAAATCCACCAGAGAGACAATGAAGGAGAATGGGGTCTTGAATGACTTTTTAAAGACACACAAGAGAGAGCCAGCTATAAAATACAACTGGAATAGTCAAAGTAACTTTGGTGTGGCCTACGAACCAATGTACCTGGATATATATTACTTTGGTGAAATCAGTATTGGAACACCACCACAAAACTTCCTAGTTGCCTTTGACACTGGTTCTTCCAATCTTTGGGTTGCCTCCACATATTGCCAGAGCCAAGCCTGCACCAATCACCCATTGTTTAACCCCAGTCTGTCCTCCACCTATACATCCAATAACCAGCAGTTCTCCATGTGGTATGGCAGTGGAAGTATGACAGGAGTGCTAGGATATGACACAGTAACAGTACAAGGTTTATCTATCCAGAATCAGGAGCTGGGACTCAGTGTCACTGAACCAAGTAGCTTCTTCTATTACTCCAAATTTGATGGTATATTTGGGATGGCCTATCAGTCACTGTCTGCGGGAGGTGCCTCTACTGCAGTGCAAGGCCTGATACAACAAAATCTCATTCCACAGCCAGTCTTTAGCTTTTACCTTACTAGCCAATCTGGAGAGGTGATATTTGGAGGAGTAGATAATAGCCTGTTCTCTGGACAGATCTACTGGACTCCTGTCACTCAGGAGATTTACTGGCAGATTGCAATTGATGAGTTCTCTGTGAATGGACAGGCAACTGGCTGGTGTAGTCAGGGATGTCAAGGCATTGTAGACACAGGAACTCCTCTGTTAACCATCCCCCAGCAGTATTTGAGCACACTGGTGCAATATGTTGGAGCACAGGAAGCACAAAATGGACAGTTTCTGGTAAATTGCAATAGTGTGCAGAACTTGCCTCCCATTAGCTTCACTATCAGTGGAATTCAGTTCTCCATTCCTCCTTCTGCATACATCCTTCAGATGAATGGATATTGTGTGGTTGGGTTTGAGTCAACATACCTTCCTTCTCGGAATGGACAACCACTGTGGATTCTGGGAGATGTTTTCCTTCGTCAGTACTACTCTGTCTATGACTTTGGCAATAATCAAGTTGGATTTGCTAGTATGGCCTAAGCCAAAGACATTTGGTAAAGGTTCTTTAAGAAGTTAGATGTCAATCTTCATACGACTACAGTAGAATTGTGATACTGTTAAGCATGCACAGTGATGAAATATACAGGACATTTAATGATACAATTACTCATATCCAAAAATAAACAAAAATGTAATAATTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGG
Protein		Refseq >NP_001015682|progastricsin (pepsinogen C) precursor [Xenopus (Silurana) tropicalis] MKWIIFTFFCLYLSEGLVRVPLKRFKSTRETMKENGVLNDFLKTHKREPAIKYNWNSQSNFGVAYEPMYLDIYYFGEISIGTPPQNFLVAFDTGSSNLWVASTYCQSQACTNHPLFNPSLSSTYTSNNQQFSMWYGSGSMTGVLGYDTVTVQGLSIQNQELGLSVTEPSSFFYYSKFDGIFGMAYQSLSAGGASTAVQGLIQQNLIPQPVFSFYLTSQSGEVIFGGVDNSLFSGQIYWTPVTQEIYWQIAIDEFSVNGQATGWCSQGCQGIVDTGTPLLTIPQQYLSTLVQYVGAQEAQNGQFLVNCNSVQNLPPISFTISGIQFSIPPSAYILQMNGYCVVGFESTYLPSRNGQPLWILGDVFLRQYYSVYDFGNNQVGFASMA

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.37511
Unigene EST Profile		EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	PGC
mouse		MGI	Pgc	All(2) Targeted, knock Out(1)
zebrafish

Publications
First:		Electron microscopic studies on the structure of motile primordial germ cells of Xenopus laevis in vitro. [J Embryol Exp Morphol 1978]
Most recent:		Developmental regulation of locomotive activity in Xenopus primordial germ cells. [Dev Growth Differ 2013]
		View All Papers 10 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		aspartic-type endopeptidase activity pepsin A activity
Biological:		proteolysis
Cellular Component:
EC:		gastricsin
KOG:		[O] Aspartyl protease

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.37511.1.S1_at
Affymetrix 2.0

Symbol legend[+]

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