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Summary Expression Gene Literature (27) GO Terms (5) Nucleotides (244) Proteins (25) Interactants (575) Wiki
XB-GENEPAGE- 5900654

Gene Symbol: cdk4

Gene Name: cyclin-dependent kinase 4

Synonyms: xcdk4
Add Xenopus synonyms , Nomenclature history


Gene Function: serine/threonine kinase

Protein Function:
Probably involved in the control of the cell cycle.


Interactants: YYY

OMIM Disease Associations: MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3; CMM3
 
Xenbase Gene ID XB-GENE-5900655 XB-GENE-5900736 XB-GENE-17346834
Gene Symbol cdk4 cdk4.L cdk4.S
Chromosome scaffold_50 Scaffold86352
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.20467 [+] Xl.46102
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 5 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cdk4 cdk4.L cdk4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CDK4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Cdk4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN cdk4 ZFIN Ensembl
chicken
fruit fly
FLYBASE Cdk4 Ensembl
worm
WORMBASE
Publications
First: Inhibition of cyclin-dependent kinases by purine analogues. [Eur J Biochem 1994]
Most recent: Sex chromosome differentiation and the W- and Z-specific loci in Xenopus laevis. [Dev Biol 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 2 terms 4 terms 0 term
EC now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
PANTHER cdk4
KEGG Pathways K02089 K02089
KOG [R] Protein kinase PCTAIRE and related kinases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 4 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF cdk4 ORF1
Affymetrix 1.0 StrJgi.5934.1.S1_at [+] Xl.4219.1.S1_at [+]
Affymetrix 2.0 Xl2.46102.1.S1_at [+]

Symbol legend[+]

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