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Summary Expression Gene Literature (1) GO Terms (35) Nucleotides (171) Proteins (62) Interactants (80) Wiki
XB-GENEPAGE-5904193
Gene Symbol:
itsn1

Gene Name:
intersectin 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
endocytic adaptor protein

Protein Function :
Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for cdc42, and thereby stimulates actin nu...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5904194 XB-GENE-5904211 XB-GENE-17339068
Gene Symbol itsn1 itsn1.L itsn1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 733480
394300
108708868
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine itsn1 itsn1.L itsn1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ITSN1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Itsn1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Itsn1 Ensembl
zebrafish
ZFIN, AGR itsn1 ZFIN Ensembl
chicken
GEISHA ITSN1 Ensembl
fruit fly
worm
Publications
First Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos., Sci Rep 2020                        
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 20 terms 0 term
PANTHER itsn1
KEGG Pathways K20045
KOG [TU] Endocytic adaptor protein intersectin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks itsn1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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