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Summary Expression Gene Literature (2) GO Terms (16) Nucleotides (195) Proteins (39) Interactants (237) Wiki
XB-GENEPAGE-5907770
Gene Symbol:
gdi1

Gene Name:
GDP dissociation inhibitor 1

Synonyms:
gdi2 ( Add synonyms , Nomenclature history )

Gene Function:
regulator of GTPase activity

Protein Function :
Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.


InterPro :
RPEL repeat , SAP dom sf , MRTF-A , SAP dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
non-syndromic X-linked intellectual disability [+]

OMIM:
METHYLMALONIC ACIDEMIA AND HOMOCYSTEINEMIA, cblX TYPE [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-5907771 XB-GENE-17338221 XB-GENE-5907787
Gene Symbol gdi1 gdi1.L gdi1.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 101731892
108698081
447577
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gdi1 gdi1.L gdi1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GDI1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gdi1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gdi1 Ensembl
zebrafish
ZFIN, AGR gdi1 ZFIN Ensembl
chicken
GEISHA GDI1 Ensembl
fruit fly
worm
Publications
First Genome evolution in the allotetraploid frog Xenopus laevis., Nature 2016                                
Most Recent A newly identified Rab-GDI paralogue has a role in neural development in amphibia., Gene 2017            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 5 terms 7 terms
PANTHER gdi1
KEGG Pathways K17255 K17255 K17255
KOG [O] RAB proteins geranylgeranyltransferase component A (RAB escort protein)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gdi1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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