[provisional- machine annotated only] Gene Symbol: kcnj5 [Predicted: Source is Human Entrez Gene] Gene Name: potassium inwardly-rectifying channel, subfamily J, member 5 [Predicted: Source is Human Entrez Gene] Synonyms: cir, girk4, katp1, kir3.4 Add Xenopus synonyms Gene Function: inward rectifier potassium channel activity Interactants: kcnj3(83) , kcnj6(27) , kcnj2(20) , cir1(14) , kcnj12(8) , kcnj1(6) , kcnj9(5) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016901|Xenopus (Silurana) tropicalis potassium inwardly-rectifying channel, subfamily J, member 5 (kcnj5), mRNA CTGCATCCTGAATCTGCTTCAGCTGCACATGCTCCCACAAGATCCATATTAACAACTGACAGAAGACGGTGCCATTATACTACACACACAGCTCTGTACATTTATAGCAGGGTCGACGTATAAATTTAACGCATCAGGGGAGGAACAGTCGGGCAGGGGGAGCGCCGGCAAGGGTCGGACTGGGCGGACCAGTCCGCGCTGCCTGTTTAACAAAACTCAGGAATATCACTGATGGAGAGACGATTTCTGATGCTGAACACAGAGATGATTCCTGAAAGAATTACACCAAGTCCACAGTGGAAAAGATTGTATGGGTCACCACAACTCATTCATTCTATCATGGCAAGGGATTTAAGGGTCTCTATGAATCAGGACTTAGAGGTTGATATTACACCCAGAGAACCCAAAAAGTTACCAAAACAAGCTCGAGAAGATCCAACACTAACAATTGACCGTACACATCTACTGTCTGAGCATAAGAAGCCAAGGCAAAGGTATATGGAAAAGGATGGAAAGTGCAATGTACACCATGGCAATGTCAAGGAAACCTACCGGTACTTTAGTGATTTGTTTACTACCCTAGTGGATCTCAAGTGGCACTTTAGCTTGTTTATCTTTACACTTGTATACACTGTCACCTGGCTTTTCTTTGGCCTTATCTGGTGGCTCATTGCATATATCCGAGGAGATCTGGACCACTTGGGCGACAAAAACTGGGTTCCATGTGTAGAAAATCTTAATGGATTTGTTTCTGCATTTCTTTTTTCTATTGAAACTGAAACTACAATTGGTTATGGCTATCGGGTTATCACAGAGAAATGCCCTGAAGGAATTGTTCTGCTTTTAGTTCAAGCCATATTGGGTTCAATTGTTAATGCCCTGATGGTAGGTTGCATGTTTGTAAAGATTAGCCAGCCAAAGAAGCGTGCTGAGACACTTATGTTCTCCAATAATGCAGTCATTTCATTAAGGGATGGAAAACTATGTTTAATGTTCCGTGTTGGGGACCTCCGAAGTTCTCACATTGTAGAAGCATCAATCCGGGCAAAACTTATTAAATCCAAGCAAACTAAAGAGGGTGAATTTATTCCACTTAATCAGACTGATATCAACGTGGGCTTTGATACAGGTGACGACCGTCTCTTTTTGGTCTCTCCTCTCATCATTTCACATGAGATTAATGAGAAAAGCCCATTCTGGGAAATGTCTCGGACTCAGATGGATATAGAAGAATTTGAAATTGTGGTTATCCTAGAGGGCATGGTGGAAGCAACAGGGATGACATGCCAAGCCCGATGCTCGTATGTGGACTCAGAAGTTCTTTGGGGACATCGCTTCACCCCAGTCCTCACTTTGGAAAAAGGATTTTATGAAGTTGACTATACCAGCTTTCATGATACCTATGAGACACCTACACCAAGTTGTAGTGCCAAAGAGTTAGATGAACTTCACCGTGGAGAACACCATACCTATACCTATGCACAAAGGAAGAACAGTGCGCAGAATGGGGCCCCTAGGTCAGAGGACTTAAACATAAGGACACAGACAGACTGAAATTTGGAAACATTTCTAAACATTTATATGCAAAACACTAGAGCAATTTTTTTATGTTCGCCTGTACTCAATGTGTAATACTGCATATTAAAGTAAATCTTGATGAAAAAAAAAAAAAAAAAA	Refseq >NM_001163392|Xenopus laevis potassium inwardly-rectifying channel, subfamily J, member 5 (kcnj5), mRNA GGAAACCACACCACTGACTTGTTTTTCAGTGAGCAGATCCTGAGCAGGTGTTGGGGGAGATTTTAGGTATATCACTGATAGAGAGGCATATTCTTATACTGAATACAAAGATGATTCCTGAAAGAATGGCACCAAGTCCTCAGTGGAAAAGATTGTATGAGTCACCACAACTCATCCAAACCATCATGGCAAGGGATTTAAGGGTCTCTATGAACCAGGACTTAAAGGTTGATATTACACCCAAAAAATTACCAAAACAAGCTCGAGAGGATCCAAAACGCAGTATTGACCGTACACATCTCCTGTTTGAGCACAAGAAGCCAAGGCAGCGGTATATGGAAAAGGATGGCAAGTGCAATGTACACCATGGCAATGTCAAGGAAACCTACCGCTACTTTAGTGATTTGTTTACTACCCTAGTGGATCTCAAGTGGCACTTTAGCTTGTTTATCTTTACACTTGTGTACACAGTCACCTGGCTTTTCTTTGGCCTTATCTGGTGGCTCATTGCTTATATCCGAGGAGATCTGGATCACTTGGGCGACAAAAACTGGGTTCCATGTGTAGAAAATCTTAATGGTTTTGTGTCTGCATTTCTTTTTTCTATTGAAACTGAGACTACAATTGGTTATGGCTATCGGGTTATCACAGAGAAATGCCCTGAAGGAATCGTTTTGCTTTTAGTTCAAGCTATATTAGGTTCCATCGTGAATGCCCTGATGGTAGGTTGCATGTTTGTAAAGATAAGCCAGCCAAAGAAGCGCGCGGAGACACTTATGTTCTCCAATAATGCTGTGATATCATTAAGGGATGGAAAACTTTGTTTAATGTTCCGCGTTGGGGACCTCAGAAGTTCTCACATTGTGGAAGCATCGATCCGGGCGAAACTTATTAAATCCAAACAAACTAAAGAAGGTGAATTTATTCCACTCAATCAGACTGATATCAACGTGGGCTTTGATACAGGCGACGATCGTCTCTTTTTGGTCTCTCCTCTCATCATTTCACATGAAATTAATGAGAAAAGCCCATTCTGGGAAATGTCTCGGACTCAGCTGGAAATAGAAGAATTTGAAATTGTGGTTATCCTAGAGGGCATGGTGGAAGCAACAGGGATGACATGCCAAGCCCGAAGCTCGTACGTGGACTCTGAAGTTCTTTGGGGACATCGATTCATCCCAGTCCTCACACTGGAAAAAGGATTTTATGAAGTGGATTATACTACTTTTCATGATAACTATGAGACACCCACTCCGAGTTGTAGTGCCAAAGAGTTGAAGGAAATTCAGCATGGAGAACAGGTCCTCCATCATACCTATACTGGGCAAAGGAAAAACAGTGCGCAGAATGGGGCCCCCTTAGGGTCAGAGGACTTAAACAGAAGAACACAGCCAGACTGAAATTTAAAAAACATTGATACATTTCTAAACATTTATATGCTCCGTACTAGCACAATTGTTTTACATCAGTCTATACTCAATGTGTAATCCTGTATATTTAGTTCAATCGTGTTGTAGGCCTCAAGTCAGTCCTCATGAGTTAAAATTATT
Protein		Refseq >NP_001016901|potassium inwardly-rectifying channel, subfamily J, member 5 [Xenopus (Silurana) tropicalis] MARDLRVSMNQDLEVDITPREPKKLPKQAREDPTLTIDRTHLLSEHKKPRQRYMEKDGKCNVHHGNVKETYRYFSDLFTTLVDLKWHFSLFIFTLVYTVTWLFFGLIWWLIAYIRGDLDHLGDKNWVPCVENLNGFVSAFLFSIETETTIGYGYRVITEKCPEGIVLLLVQAILGSIVNALMVGCMFVKISQPKKRAETLMFSNNAVISLRDGKLCLMFRVGDLRSSHIVEASIRAKLIKSKQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRTQMDIEEFEIVVILEGMVEATGMTCQARCSYVDSEVLWGHRFTPVLTLEKGFYEVDYTSFHDTYETPTPSCSAKELDELHRGEHHTYTYAQRKNSAQNGAPRSEDLNIRTQTD	Refseq >NP_001156864|potassium inwardly-rectifying channel, subfamily J, member 5 [Xenopus laevis] MIPERMAPSPQWKRLYESPQLIQTIMARDLRVSMNQDLKVDITPKKLPKQAREDPKRSIDRTHLLFEHKKPRQRYMEKDGKCNVHHGNVKETYRYFSDLFTTLVDLKWHFSLFIFTLVYTVTWLFFGLIWWLIAYIRGDLDHLGDKNWVPCVENLNGFVSAFLFSIETETTIGYGYRVITEKCPEGIVLLLVQAILGSIVNALMVGCMFVKISQPKKRAETLMFSNNAVISLRDGKLCLMFRVGDLRSSHIVEASIRAKLIKSKQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRTQLEIEEFEIVVILEGMVEATGMTCQARSSYVDSEVLWGHRFIPVLTLEKGFYEVDYTTFHDNYETPTPSCSAKELKEIQHGEQVLHHTYTGQRKNSAQNGAPLGSEDLNRRTQPD

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.27347	Xl.23590
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	KCNJ5
mouse		MGI	Kcnj5	All(5) Targeted, knock Out(1) Targeted, other(3)
zebrafish

Publications
First:		Functional characterization and localization of a cardiac-type inwardly rectifying K+ channel. [Receptors Channels 1995]
Most recent:		Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma. [J Hypertens 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		G-protein activated inward rectifier potassium channel activity inward rectifier potassium channel activity potassium channel activity
Biological:		potassium ion transport
Cellular Component:		membrane
EC:
KOG:		[P] Inward rectifier K+ channel

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.27347.1.S1_at	Xl.23590.1.S1_at
Affymetrix 2.0			Xl2.23590.1.S1_at

Symbol legend[+]

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