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Summary Expression Gene Literature (158) GO Terms (18) Nucleotides (88) Proteins (21) Interactants (127) Wiki
XB-GENEPAGE- 5921461

Gene Symbol: kcnq1

Gene Name: potassium channel, voltage gated KQT-like subfamily Q, member 1

Synonyms: kv7.1
Add Xenopus synonyms , Nomenclature history


Gene Function: voltage-gated potassium channel activity

Protein Function:
Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon. Associates with KCNE beta subunits that modulates current kinetics. Induces a volta...[+]


Interactants: YYY

OMIM Disease Associations: ATRIAL FIBRILLATION, FAMILIAL, 3; ATFB3 [+]
1/4
 
Xenbase Gene ID XB-GENE-5921462 XB-GENE-5921471 XB-GENE-17332712
Gene Symbol kcnq1 kcnq1.L kcnq1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.48242 [+] Xl.21509
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine kcnq1 kcnq1.L kcnq1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KCNQ1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Kcnq1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN kcnq1 ZFIN Ensembl
chicken
GEISHA KCNQ1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: I(sK) Channel in Strial Marginal Cells. Voltage-Dependence, Ion-Selectivity, Inhibition by 293B and Sensitivity to Clofilium. [ 1997]
Most recent: Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome. [Cell 2017]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 18 terms 0 term
EC
PANTHER kcnq1
KEGG Pathways K04926
KOG [P] Voltage-gated K+ channel KCNQ
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Kcnq1 Ab1 , Kcnq1 Ab2 Kcnq1 Ab1 , Kcnq1 Ab2
Affymetrix 1.0 StrJgi.2763.1.S1_s_at [+] Xl.21509.1.S1_at [+]
Affymetrix 2.0 Xl2.42496.1.A1_at [+]

Symbol legend[+]

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