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Summary Expression Gene Literature (167) GO Terms (24) Nucleotides (96) Proteins (28) Interactants (317) Wiki
XB-GENEPAGE-5921461
Gene Symbol: kcnq1

Gene Name: potassium channel, voltage gated KQT-like subfamily Q, member 1

Synonyms: kv7.1 ( Add synonyms , Nomenclature history )

Gene Function: voltage-gated potassium channel activity

Protein Function :
Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon. Associates with KCNE beta subunits that modulates current kinetics. Induces a volta...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: familial atrial fibrillation [+]

OMIM: ATRIAL FIBRILLATION, FAMILIAL, 3; ATFB3 [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-5921462 XB-GENE-5921471 XB-GENE-17332712
Gene Symbol kcnq1 kcnq1.L kcnq1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100145329
373746
108715189
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine kcnq1 kcnq1.L kcnq1.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KCNQ1 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Kcnq1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR kcnq1.1 ZFIN Ensembl
chicken
GEISHA KCNQ1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy., J Biol Chem 1998  
Most Recent ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling., Elife 2019                      
All View All Papers 2 paper(s) referencing morpholinos 10 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 19 terms 0 term
PANTHER kcnq1
KEGG Pathways K04926
KOG [P] Voltage-gated K+ channel KCNQ
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks kcnq1
Antibodies Kcnq1 Ab1 , Kcnq1 Ab2 Kcnq1 Ab1 , Kcnq1 Ab2
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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