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Summary Expression Gene Literature (161) GO Terms (21) Nucleotides (91) Proteins (22) Interactants (306) Wiki
XB-GENEPAGE- 5921461

Gene Symbol: kcnq1

Gene Name: potassium channel, voltage gated KQT-like subfamily Q, member 1

Synonyms: kv7.1
Add Xenopus synonyms , Nomenclature history


Gene Function: voltage-gated potassium channel activity

Protein Function :
Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon. Associates with KCNE beta subunits that modulates current kinetics. Induces a volta...[+]


Interactants: Loading ...

Disease Ontology:
   FAMILIAL ATRIAL FIBRILLATION [+]

OMIM Diseases:
   ATRIAL FIBRILLATION, FAMILIAL, 3; ATFB3 [+]
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Xenbase Gene ID XB-GENE-5921462 XB-GENE-5921471 XB-GENE-17332712
Gene Symbol kcnq1 kcnq1.L kcnq1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.48242 [+] Xl.21509
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine kcnq1 kcnq1.L kcnq1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KCNQ1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Kcnq1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR kcnq1 ZFIN Ensembl
chicken
GEISHA KCNQ1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: I(sK) Channel in Strial Marginal Cells. Voltage-Dependence, Ion-Selectivity, Inhibition by 293B and Sensitivity to Clofilium. [Audit Neurosci 1997]
Most recent: Unexplained cardiac arrest: a tale of conflicting interpretations of KCNQ1 genetic test results. [Clin Res Cardiol 2018]
View All Papers 2 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 10 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 19 terms 0 term
PANTHER kcnq1
KEGG Pathways K04926
KOG [P] Voltage-gated K+ channel KCNQ
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Kcnq1 Ab1 , Kcnq1 Ab2 Kcnq1 Ab1 , Kcnq1 Ab2
Affymetrix 1.0 StrJgi.2763.1.S1_s_at [+] Xl.21509.1.S1_at [+]
Affymetrix 2.0 Xl2.42496.1.A1_at [+]

Symbol legend[+]
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