Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (17) GO Terms (6) Nucleotides (62) Proteins (30) Interactants (549) Wiki
XB-GENEPAGE-5938587
Gene Symbol:
erbb2

Gene Name:
erb-b2 receptor tyrosine kinase 2

Synonyms:
XerbB2 ( Add synonyms , Nomenclature history )

Gene Function:
epidermal growth factor receptor

Protein Function :


InterPro :
Leu-rich rpt , LRR dom sf , Leu-rich rpt typical-subtyp

Interactants:
Loading ...

Diseases: 


Disease Ontology:
stomach cancer [+]

OMIM:
GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC [+]

External Links:
 
Xenbase Gene ID XB-GENE-5938588 XB-GENE-17331738 XB-GENE-5938594
Gene Symbol erbb2 erbb2.L erbb2.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492078
108700774
108702492
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine erbb2 erbb2.L erbb2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ERBB2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Erbb2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Erbb2 Ensembl
zebrafish
ZFIN, AGR erbb2 ZFIN Ensembl
chicken
GEISHA ERBB2 Ensembl
fruit fly
worm
Publications
First Expression of Wnt5a is downregulated by extracellular matrix and mutated c-Ha-ras in the human mammary epithelial cell line MCF-10A., Biochem Biophys Res Commun 1997  
Most Recent Opposite T3 Response of ACTG1-FOS Subnetwork Differentiate Tailfin Fate in Xenopus Tadpole and Post-hatching Axolotl., Front Endocrinol (Lausanne) 2019                
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 6 terms 6 terms
PANTHER erbb2
KEGG Pathways K05083 K05083 K05083
KOG [T] Epidermal growth factor receptor EGFR and related tyrosine kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks erbb2
Morpholinos (on-target & off-target) erbb2 MO1
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info