Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (2) GO Terms (10) Nucleotides (494) Proteins (37) Interactants (84) Wiki
Gene Symbol:

Gene Name:
uroplakin 1A

up1a , upia , upka , tspan21 ( Add synonyms , Nomenclature history )

Gene Function:
Tetraspanin family integral membrane protein

Protein Function :

Loading ...


External Links:
Xenbase Gene ID XB-GENE-5940083 XB-GENE-5940464 XB-GENE-17335361
Gene Symbol upk1a upk1a.L upk1a.S
Chromosome scaffold_6491 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 4.1 Version 9.2 Version 9.2
CDS Gene model Gene model
Entrez Gene 448032
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine upk1a upk1a.L upk1a.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards UPK1A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Upk1a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Upk1a Ensembl
ZFIN, AGR upk1a ZFIN Ensembl
fruit fly
First Origin of the tetraspanin uroplakins and their co-evolution with associated proteins: implications for uroplakin structure and function., Mol Phylogenet Evol 2006  
Most Recent Uroplakins play conserved roles in egg fertilization and acquired additional urothelial functions during mammalian divergence., Mol Biol Cell 2018                    
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 1 terms 1 terms
KEGG Pathways K17347 K17347 K17347
KOG [R] Tetraspanin family integral membrane protein
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks
ORFs upk1a ORF1 upk1a.L ORF1 upk1a.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556