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Summary Expression Gene Literature (2) GO Terms (3) Nucleotides (139) Proteins (28) Interactants (422) Wiki
XB-GENEPAGE-5998209
Gene Symbol:
plekhg4

Gene Name:
pleckstrin homology and RhoGEF domain containing G4

Synonyms:
sca4 , prtphn1 , arhgef44 ( Add synonyms , Nomenclature history )

Gene Function:
Multidomain protein, contains SPEC repeats, PH, SH3, and separate rac-specific and rho-specific guanine nucleotide exchange factor domains

Protein Function :



Interactants:
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Diseases: 


Disease Ontology:
spinocerebellar ataxia type 4 [+]

OMIM:
SPINOCEREBELLAR ATAXIA 31; SCA31 [+]

External Links:
 
Xenbase Gene ID XB-GENE-5998210 XB-GENE-5865153 XB-GENE-17330106
Gene Symbol plekhg4 plekhg4.L plekhg4.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 779571
446633
108715478
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq RefSeq NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine plekhg4 plekhg4.L plekhg4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PLEKHG4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Plekhg4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Plekhg4 Ensembl
zebrafish
ZFIN, AGR plekhg4 ZFIN Ensembl
chicken
GEISHA PLEKHG4 Ensembl
fruit fly
worm
Publications
First Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Mech Dev 1998                                                              
Most Recent An atlas of differential gene expression during early Xenopus embryogenesis., Mech Dev 2005                                                                                                                                                          
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 3 terms 3 terms
PANTHER plekhg4
KEGG Pathways K23860 K23860
KOG [T] Multidomain protein, contains SPEC repeats, PH, SH3, and separate rac-specific and rho-specific guanine nucleotide exchange factor domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks plekhg4
ORFs plekhg4.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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