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Summary Expression Gene Literature (0) GO Terms (0) Nucleotides (102) Proteins (26) Interactants (1) Wiki
XB-GENEPAGE-6035125
Gene Symbol:
szt2

Gene Name:
SZT2, KICSTOR complex subunit

Synonyms:
SZT2A , SZT2B , EIEE18 , C1orf84 , KIAA0467 ( Add synonyms , Nomenclature history )

Gene Function:
Nucleolar GTPase/ATPase p130. he protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]

Protein Function :



Interactants:
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Diseases: 


Disease Ontology:
Ohtahara syndrome

OMIM:
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 18; EIEE18

External Links:
 
Xenbase Gene ID XB-GENE-6035126 XB-GENE-6487217 XB-GENE-17338326
Gene Symbol szt2 szt2.L szt2.S
Chromosome Chr04 Scaffold8916
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 6.0
CDS Gene model
Entrez Gene 100496044
mRNA NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine szt2 szt2.L szt2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SZT2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Szt2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Szt2 Ensembl
zebrafish
szt2 Ensembl
chicken
GEISHA SZT2 Ensembl
fruit fly
worm
Publications
First
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 0 term 0 term
PANTHER szt2
KEGG Pathways
KOG [Y] Nucleolar GTPase/ATPase p130
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks szt2
Clones Horizon Source BioScience Source BioScience
Plasmids Addgene Addgene

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