Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (6) GO Terms (4) Nucleotides (48) Proteins (22) Interactants (155) Wiki
XB-GENEPAGE-6049122
Gene Symbol:
ern1

Gene Name:
endoplasmic reticulum to nucleus signaling 1

Synonyms:
ire1 , ire1p , ire1a , ire1 alpha , xIRE1 ( Add synonyms , Nomenclature history )

Gene Function:
Serine/threonine protein kinase and endoribonuclease ERN1/IRE1, sensor of the unfolded protein response pathway

Protein Function :


Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-6049123 XB-GENE-17339046 XB-GENE-6486419
Gene Symbol ern1 ern1.L ern1.S
Chromosome scaffold_7121 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 7.1 Version 9.2 Version 9.2
CDS Gene model Gene model
Entrez Gene 108701211
108702862
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ern1 ern1.L ern1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ERN1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ern1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ern1 Ensembl
zebrafish
ZFIN, AGR ern1 ZFIN Ensembl
chicken
GEISHA ERN2 Ensembl
fruit fly
worm
Publications
First Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis., Mech Dev 2006                                                    
Most Recent IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis., J Biomed Res 2014          
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 4 terms 4 terms
PANTHER ern1
KEGG Pathways
KOG [T] Serine/threonine protein kinase and endoribonuclease ERN1/IRE1, sensor of the unfolded protein response pathway
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks
Morpholinos ern1 MO1 , ern1 MO2 ern1 MO1 , ern1 MO2 ern1 MO1 , ern1 MO2
Clones Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556