Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (5) GO Terms (3) Nucleotides (95) Proteins (20) Interactants (123) Wiki
XB-GENEPAGE-6052257
Gene Symbol:
knl1

Gene Name:
kinetochore scaffold 1

Synonyms:
casc5 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
microcephaly

OMIM:
MICROCEPHALY 4, PRIMARY, AUTOSOMAL RECESSIVE; MCPH4

External Links:
 
Xenbase Gene ID XB-GENE-6052258 XB-GENE-6486626 XB-GENE-17343855
Gene Symbol knl1 knl1.L knl1.S
Chromosome Chr8 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.1
CDS Gene model
Entrez Gene 100497601
mRNA RefSeq
Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine knl1 knl1.L knl1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KNL1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Knl1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Knl1 Ensembl
zebrafish
ZFIN, AGR knl1 ZFIN Ensembl
chicken
GEISHA KNL1 Ensembl
fruit fly
worm
Publications
First Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly., J Cell Biol 2008                  
Most Recent Micromanaging checkpoint proteins., Elife 2017    
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 3 terms 0 term 0 term
PANTHER knl1
KEGG Pathways K11542
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks knl1
Clones Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556