myc Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

Gene Literature (322)

XB-GENEPAGE-6052813

[provisional- machine annotated only]

Gene Symbol: myc [Predicted: Source is Human Entrez Gene]

Gene Name: v-myc myelocytomatosis viral oncogene homolog [Predicted: Source is Human Entrez Gene]

Synonyms: c-myc, cmyc, Xcmyc, X-cmyc Add Xenopus synonyms

Gene Function: transcription factor

Interactants: t(43) , chrd(36) , sox2(32) , otx2(28) , snai2(28) , odc1(26) , wnt8a(24) View All

1/3

XB-GENE-6052814

XB-GENE-6053022

XB-GENE-6256575

Molecules	tropicalis	laevis a	laevis b
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene	Entrez Gene
mRNA	Refseq >NM_204059\|Xenopus (Silurana) tropicalis uncharacterized protein MGC76254 (MGC76254), mRNA GCGGGGAGCGAGTGGGGAAGCTTGTGGTCCGGCTGCTGCTGCTATTACTGCAGGAGGAGGAGTGGGAATCGCAGCGACATTGAAAGCCCCGCCGGCTCTGAGAGAGAAGGGAGAGGCACGACAGCCTGTGGATTTACAAGCGCTACAGCTTCATTATTCGGACTATTGGAAGTGTATCCCGGCATTGCTTGGGAGACCACTCGGAGGGGAGGAAGGATGCCTCTTAATGCCAATTTCCCCAGCAAGAACTACGACTACGACTATGACTTGCAGCCCTGCTTCTTCTTTCTGGAGGAGGAGAACTTCTACCACCAGCAAAGCCGACTGCAGCCGCCGGCCCCCAGTGAGGACATCTGGAAGAAGTTTGAGCTGCTCCCCACCCCACCCCTGTCACCCAGCCGCAGATCCAGCCAGTCCAGCCTTTTCCCCTCTACGGCTGATCAGCTGGAGATGGTGACCGAATTCCTGGGAGGGGACATGGTCAACCAGAGCTTTATCTGCGAGGCGGACGATGAAGCCTTGCTGAAGTCTATCGTCATACAGGACTGTATGTGGAGCGGCTTCTCGGCGGCAGCCAAGCTTGAGAAAGTGGTATCTGAGAAGCTGGCATCCTACCAGGCTTCTAGGAAAGAGAGTGCTCTGTCTTCTTCTCAGTGCCAGAGTCCACCAGAGCAGAGCCCACTTAAGTCTCCTTCATGCCATGGGAGCCTCAGTCTCGGAGGGACTCGGAGCAGCCATGGATTCCTCCAGGACCCCAGCTCGGATTGTGTTGACCCTTCGGTGGTTTTCCCATACCCTCTGAATGACAGCATTTCCAACGCCAGCTCACCTTGCCAAGACCTCATGTTGGAAACGCCACCGATCAGCAGCAACAGCAGCAGCAGTGAATCAGAAGAGGAACCGGAAGACGAGGATGAAGACTGTGATGAGGAAGAAGAGATTGATGTTGTCACGGTGGAAAAAAGGCAGACGGCATCCAAGCGAATGGAATCCAGCTCTCACTCGCAGCCATCTAGACCCCACCACAGCCCATTAGTTCTGAAGAGGTGTCACGTTCCCATTCACCAACACAACTACGCAGCGTCCCCCTCAACCAAAGTGGACTATGTTTCTTCCAAGAGGGCGAAGCTAGAAAGCAACGCCAGGGTCCTCAAACAGATCAGCAATAACCGCAAGTGCAGCAGTCCCAGGTCCTCTGATTCCGAAGAGAACGACAAGAGGCGGACACACAACGTTTTAGAGCGTCAGAGGCGGAACGAGCTCAAGTTGAGCTTCTTCGCCCTGCGCGACCAGGTACCGGAGGTGGCCAATAACGAGAAGGCGCCCAAAGTCGTCATCCTCAAAAAGGCAACAGAATACGTCGTTTCTATGCAGGAGGATGAGCGACGGCTCATACGGGAAACAGAACAGTTAAAGTACAGGAGAGAGCAGTTAAAACAGAGACTGCAACAGCTAAGGAACTTGGTTGTCTAAATAACAAACTCTTTATTTACACTTTATAAACTGTGACAGTCTATATCAAGGTTGTCTCTTCCTCGAGACCTACTACAAAACTGATTTTGTAGAACACGGACAACTGCATGCAGATGATTTCACAACTACACAACCTTGGCATGGTCTCAGATTCTGCCAGCACCTTAAAACTGCCTCAATACTGGGATTTGGGTATTATGGGACTGTTTTGTTTTTTTTTGTTTTCCTGCTTGAGGGGTATATTTGCCAACTTTTTGTTGTTATTGTTGTTTTACAACCTTTGTATTTAAAACATTTATTTTTCTTATAAACAAACAAATTCCTGAAGTTTGGCTCTAAATAGCTTAAATATATACATCATCGCTGACTCATCTATAATATCATTAATAGATCGTTATAGAAATTATTGTATTCACTTCTCTAACAGCTATGGCGCAAGAAAAAAAAAAAAAGTGCAAAACTTTGGTGTTTTGCTGCCATGACGCATTTAATGAACTTTTTATGTTTTCGTTTATTTAAAAAAAAAAAACATTTATCTTCGAGTTTCATTTGGATAATTCTGTATTGGAGCTAGTTGTACCAGTTTCTGAAGAACTGATGAAGAAGGCACTGACCAACATGTATCTAAAAAATGCTAAAAGTACATAATATTATCCCATCCCCTGTATCCTCGTCATATGAAAAACCCTCTAACCTGCTGGCTGCTCAAGGCGTCCTGTTGTAGCGGCAGGGTAGTGGTCTTTCCTAGCAACACAGACGCGGTCTGCTGTTTCTATATTGATTCTCTTAAAGATATTATAACATGCTGGTCTGAAAAATTCATCATTTGTTTGGCTTGTTTTACTTAAGATGAAACTATTCAGATGGGGCTCCAACATCCCATAATGATATAGTGACTTTTAACATGGCAAGCTGTTTGGAATAAGCTTCAGAAAATAAAAATCAAGTTAAAAAAATAAACACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001085896\|Xenopus laevis Transcriptional regulator Myc-A (myc-a), mRNA ACAAGGGAGAGGCAGCCTGTGGATTTATAAACGCGACCAAAGGAATATTGGACTCGTATTATCCCGGGATTAGACGGGAGACCAATCGCATGGCAGGAAAGATGCCTCTTAATGCCAATTTTCCCAGCAAGAACTACGACTACGATTATGACTTGCAGCCCTGCTTCTTCTTTCTGGAGGAGGAGAACTTCTACCACCAGCAAAGCCGACTGCAGCCGCCGGCCCCCAGTGAGGACATCTGGAAGAAGTTTGAGCTGCTCCCCACCCCGCCCTTGTCACCCAGCCGCAGATCCAGCCAGTCCAGCCTTTTCCCCTCCACGGCTGATCAGCTGGAGATGGTGACCGAATTCCTGGGAGGGGACATGGTCAACCAGAGCTTTATCTGCGAGGCGGATGACGAAGCCTTGCTGAAGTCCATCGTCATACAGGACTGTATGTGGAGTGGATTTTCGGCTGCGGCCAAGCTGGAGAAAGTGGTGTCTGAGAAGCTGGCGTCCTACCAGGCTTCTAGGAAAGAGAGTGCTCTGTCTTCTTCTTCTCCGTGTCCGAGTCAACCACCACCGAGCCCGCTTAAGTCTCCCTCGTGTCATGGGAGCCTGAGTCTGGGAGGGACCCACAGGAGCAGCCATGGTTTTCTCCAGGACCCCAGCTCGGATTGTGTTGACCCTTCAGTGGTCTTCCCATACCCACTGAACGACAGCATTTCCAACGCCAGCTCTCCTTGCCAAGATCTCATTTTGGAAACACCGCCCATCAGCAGTAACAGCAGCAGCAGTGAATCTGAAGAGGAACCAGAAGATGAGGATGAAGACTGCGACGAGGAAGAGGAGATTGACGTTGTCACAGTAGAAAAAAGGCAGTCGGCATCCAAGCGGGTGGAATCCAGTTCTCATTCGCAGCCCTCCCGACCCCACTACAGCCCTTTAGTTCTGAAGCGGTGTCACGTTCCCATTCACCAACACAACTACGCGGCGTCTCCCTCGACCAAAGTGGACTATGTTTCTTCCAAAAGGGCGAAACTAGAAAGCAACATCCGGGTCCTCAAACAGATCAGCAACAACCGCAAGTGCGCCAGTCCCAGGTCCTCGGATTCCGAAGAGAACGACAAGAGGAAGACGCACAACGTTCTGGAGCGCCAGAGGCGGAACGAGCTCAAGTTGAGTTTTTTTGCCTTGCGCGATCAGGTACCGGAGGTGGCGAGCAACGAGAAGGCCCCCAAAGTAGTCATCCTCAAAAAGGCAACGGAATACGCCATTTCTCTGCAGGAGGACGAACGGCGGCTCATACGGGAAACAGAACAGTTAAAGTACAGGAAAGAGCAGTTAAAACAGAGACTCCAACAGCTGAGGAACTTTGTCTAATTCACAAACTCTTATTTAACACTTTATATAAACTGTGACAGTCTATATCAAGGTTGTCTCTTCCTCGAGACCGACTACAAAACTGAATTTGTAGAACATGGACAACTGCATGCAGATGATTTCACAACTACACAACCTTGGCATGGTCTCAAACCGATTCTGCCAGCACCTTAAAACTGCCTCAATACTGGGATTTGGGTATTATGGGACTTTGTTTTTTTTTTTTTTTTTCTTGCTTGAGGGGGTATATTTGCCAACTTTTTGTTTGTTTGTTTGTTATTATTGTTTTTACAACCTTTTGTATTTAAAACATTTATTTTTCTTATAAACAAATTCCTGAAGTTTGGCTCTGAATAGCTTAAATATATATATCATCGCTGACTCGTCTATAATATCATTGATAGAACATTATAGAAATTATTGTATTCACTTCTAACCGCTATGGCGCAAAAAAAAAAAGCAAAAACGTTTTTGCTAATTCGTACCATGAACGCATTTAATGAACTTTTATTTTAAGAAGAAAAAAACATTTAATCTTTCAAGTTTCATTTGAATAATTCTGTATTGGAGCTAGTTGTACCAGTTTCTGAAGAACTGATGAAGAAGGCACTGACCAACATGTAATTTAAAAAAGAAAATACTAAAAGTACTTAATATCCCCATACCCTGTATCCTTGTCATGTGGAAACCTCTAACCTGCTGGCTGCTCCTGGTGTCCTGTTGTAATAGCAGCAGCAGGATCTTGGTCTTTCCTAGTAACACAGAAGCAGTCTGCTGTTTCTATATTGATTCTCTTAAAGATATTATAACATGCTGGTCTGAAAAAAAAAAACTCATCATTCGTTTATTGTAAAGCTTGCTTTGCTTAAGATGAAACTATTCACATTGGGGGCCAACCCCCCATAATGATATAGTGACTTAACATAGCAAGCTGTTTGGAATAAGCTTCAGAAAATAAAAATCAACTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001090653\|Xenopus laevis proto-oncogene c-myc II (myc), mRNA GAATTCGAGACCGGCGCTATATAAGGCTCGCTGGCTGCTTTTTTGCTGCCAGTCTGTGTGCGGGGAGCGAGTGGGAAGCTTGTGATACAACGAGAGGAGAGGGAGGGAGTCAAAGCGTCGGCTCAGCCTGTGGATTTACAAGCGCGACAGCTCTCATTAGGAAACCTTGGACTTGTATCCCGGCTTTGCACGGGAGACCACTCGGAGGGCAGGAAAGATGCCTCTTAACGCCAATTTTCCCAGCAAGAACTACGACTACGATTATGACTTGCAGCCCTGCTTCTTCTTTCTGGAGGAGGAGAACTTCTACCACCAGCAAAGCCGACTGCAGCCGCCGGCCCCCAGTGAGGACATCTGGAAGAAGTTTGAGCTGCTCCCCACCCCGCCCTTGTCACCCAGCCGGAGATCCAGCCAGTCCAGCCTTTTCCCCTCTACGGCTGATCAGCTGGAGATGGTGACCGAATTCCTGGGAGGGGACATGGTCAACCAGAGCTTTATCTGTGAGGCGGATGACGAAGCCTTGCTGAAGTCCATAGTCATACAGGACTGTATGTGGAGTGGCTTCTCGGCGGCGGCCAAGCTGGAGAAAGTGGTGTCTGAGAAGCTGGCGTCATACCAGGCTTCTAGGAAAGAGAGTGCTCTGTCTACTTCTCAGTGCCAGAGTCAACCGCCACAGAGCCCTCTTAAATCTCCCTCGTGTGATGGGAGCTTAAATCTCGGAGGGACCAACAGGAGCAGCCATGAATTCCTCCAAGACCCCAGCTCGGATTGGGTTGACCCTTCAGTGGTCTTCCCATACCCACTGAACGACAGCATTTCCAACGCCAGCTCACCTTGCCAAGATCTCATGTTGGAAACACCACCCATCAGCAGCAACAGCAGCAGTAGTGAATCAGAAGACGAACAGGAAGACGATGACGACGATGAAGACTGCGACGAGGAAGAGGAGATTGACGTTGTCACGGTAGAAAAAAGGCAGACGGCGTCTAGGCGGATGGAATCCGGTTCTCATTCGCAGTCCTCCCGACCCCACCACAGCCCGTTAGTTCTGAAGCGGTGTCACGTTCCCATTCACCAACACAACTACGCGGCATCTCCCTCAACCAAAGTGGACTATGTTTCTTCCAAGAGGGCGAAACTAGAAAGCAACGTCCGGGTCCTCAAACAGATCAGCAATAACCGCAAGTACGCCAGCCCCAGGTCCTCGGATTCCGAAGAGAACGACAAGAGGCGGACGCACAACGTTTTAGAGCGTCAGAGGCGGAACGAGCTTAAGTTGAGTTTCTTCGCCTTGCGAGACCAGGTACCCGAGGTGGCGAACAACGAGAAGGCCCCCAAAGTCGTCATCCTCAAAAAGGCAACGGAATACGCAATTTCTATGCAGGAGGACGAGCGACGGCTCATACGGGAAACAGAACAGTTAAAGTACAGGAAAGAGCAGTTAAAACAGAGACTCCAACAGCTAAGGAACTCTGTCTAATTCACAAACTCTTATTTACACTTTATATATAAACTGTGACCGTCTATATCAAGGTTGTCTCTTCCTCGAGACAGACTTACAAAACTGAATTTGTAGAACATGGACAACTGCATGCAGATGATTTCACAACTACACAACCTTGGCATGGTCTCAAACAGATTCTGCCAGCACTTAAAACTGCCTCAATACTGGGATTTGGGTATTATGGGACTGTTTGTAATTTTTTTTTTTTTTTTTTTGCTTATTTTTGTTTGTTTGTTATTGTTGTTTTACAACCTTTGTATTTAAAACATTTATTTTTCTTATAAACAAATTCCTGAAGTTTGCCTCTGAATAGCTTACATATATATCCATCGTTGCTGACTCGTCTATAATATCATTAATAGATCGTTATAGAAATTATTGTATTCACTTCTAACCGCTATGGCGCAAAAGAAAAGAAAAAAGCAAAACTATTTTTTTTTGTGTTTTGCTAATTAGTACCATGAACGCATTTAACGGACTTTTTTTATGTTTTGTTGATTTTAAAAAGAAAAGAATTAACATTTTTATCTTTTCAAGTTTCATTTGGATAATTCTGTATTGGAGCTAGTCGTACCAGTTTCTGAAGAACTGATGAAGAAGGCACTGACCAACATGTAATTTCAAAAAAATACTAAAAGTACTTAATATTATCCCATACCCTGTATCCTTGTCATGTGAAAACCCCTAACCTGCTGGCTGCTCATGGTGTCCTGTTGTAGTAGCAGCAGCAGGATAATGGTCTTTCCTAGTAACACAGAAGCAGTCTGATGATGTTTCTATATTGATTCTCTTAAAGATATTATAACATGCTGGTCTGAAAAATTCATCATTTGTTTATTGTAAGGCTTGTTTTTGCTTAAGATGAAACTATTCACGTGGGGTCCGACCTCCCGTAAGGATAGTGACATTTAACATGGCAAGCTGTTTGGAATTGGAAGCTTCAGAAAATAAAAAATCAAGTTAAAAAAAAAAAAAAAAAAAAA
Protein	Refseq >NP_989390\|uncharacterized protein LOC395024 [Xenopus (Silurana) tropicalis] MPLNANFPSKNYDYDYDLQPCFFFLEEENFYHQQSRLQPPAPSEDIWKKFELLPTPPLSPSRRSSQSSLFPSTADQLEMVTEFLGGDMVNQSFICEADDEALLKSIVIQDCMWSGFSAAAKLEKVVSEKLASYQASRKESALSSSQCQSPPEQSPLKSPSCHGSLSLGGTRSSHGFLQDPSSDCVDPSVVFPYPLNDSISNASSPCQDLMLETPPISSNSSSSESEEEPEDEDEDCDEEEEIDVVTVEKRQTASKRMESSSHSQPSRPHHSPLVLKRCHVPIHQHNYAASPSTKVDYVSSKRAKLESNARVLKQISNNRKCSSPRSSDSEENDKRRTHNVLERQRRNELKLSFFALRDQVPEVANNEKAPKVVILKKATEYVVSMQEDERRLIRETEQLKYRREQLKQRLQQLRNLVV	Refseq >NP_001079365\|similar to myelocytomatosis oncogene [Xenopus laevis] MPLNANFPSKNYDYDYDLQPCFFFLEEENFYHQQSRLQPPAPSEDIWKKFELLPTPPLSPSRRSSQSSLFPSTADQLEMVTEFLGGDMVNQSFICEADDEALLKSIVIQDCMWSGFSAAAKLEKVVSEKLASYQASRKESALSSSSPCPSQPPPSPLKSPSCHGSLSLGGTHRSSHGFLQDPSSDCVDPSVVFPYPLNDSISNASSPCQDLILETPPISSNSSSSESEEEPEDEDEDCDEEEEIDVVTVEKRQSASKRVESSSHSQPSRPHYSPLVLKRCHVPIHQHNYAASPSTKVDYVSSKRAKLESNIRVLKQISNNRKCASPRSSDSEENDKRKTHNVLERQRRNELKLSFFALRDQVPEVASNEKAPKVVILKKATEYAISLQEDERRLIRETEQLKYRKEQLKQRLQQLRNFV UniProtKB	Refseq >NP_001084122\|transcriptional regulator Myc-B [Xenopus laevis] MPLNANFPSKNYDYDYDLQPCFFFLEEENFYHQQSRLQPPAPSEDIWKKFELLPTPPLSPSRRSSQSSLFPSTADQLEMVTEFLGGDMVNQSFICEADDEALLKSIVIQDCMWSGFSAAAKLEKVVSEKLASYQASRKESALSTSQCQSQPPQSPLKSPSCDGSLNLGGTNRSSHEFLQDPSSDWVDPSVVFPYPLNDSISNASSPCQDLMLETPPISSNSSSSESEDEQEDDDDDEDCDEEEEIDVVTVEKRQTASRRMESGSHSQSSRPHHSPLVLKRCHVPIHQHNYAASPSTKVDYVSSKRAKLESNVRVLKQISNNRKYASPRSSDSEENDKRRTHNVLERQRRNELKLSFFALRDQVPEVANNEKAPKVVILKKATEYAISMQEDERRLIRETEQLKYRKEQLKQRLQQLRNSV UniProtKB

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny

Expression	tropicalis	laevis a	laevis b
UniGene	Str.1141 [+] Str.45920	Xl.826 [+] Xl.36244	Xl.1155
Unigene EST Profile	EST Profile	EST Profile	EST Profile
GEO data		GEO	GEO
Images	62 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	MYC	OMIM:113970
mouse	MGI	Myc	All(22) Targeted, knock Out(7) Targeted, other(11)
zebrafish	ZFIN ZFIN	myca mycb

Publications
First:		Accurate and efficient transcription of human c-myc genes injected into Xenopus laevis oocytes. [Mol Cell Biol 1985]
Most recent:		Expression of cyclin D1, cyclin D2, and N-myc in embryos of the direct developing frog Eleutherodactylus coqui, with a focus on limbs. [Gene Expr Patterns 2013]
		View All Papers 72 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:

Reagents	tropicalis	laevis a	laevis b
Clones		EXRC - 1 clone(s)
	open biosystems	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.1141.1.S2_at [+] Str.1141.1.S1_a_at Str.45920.1.A1_at	Xl.826.3.S1_x_at [+] Xl.826.2.S1_x_at Xl.826.1.S1_x_at	Xl.1155.2.S1_x_at [+] Xl.1155.1.S1_x_at
Affymetrix 2.0		Xl2.826.3.S1_x_at [+] Xl2.826.2.S1_x_at Xl2.826.4.A1_at Xl2.826.4.S1_a_at Xl2.826.1.S1_x_at	Xl2.1155.2.S1_x_at [+] Xl2.1155.1.S1_x_at

Symbol legend[+]