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Summary Expression Gene Literature (51) GO Terms (2) Nucleotides (22) Proteins (7) Interactants (259) Wiki
XB-GENEPAGE-6054494
Gene Symbol:
ptpn11

Gene Name:
protein tyrosine phosphatase, non-receptor type 11

Synonyms:
cfc , shp2 , bptp3 , ptp2c , ns1 , shp-2 , ptp-2 , ptpn11-a , ptpn11-b ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :


Interactants:
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Diseases: 


Disease Ontology:
juvenile myelomonocytic leukemia [+]

OMIM:
JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML [+]

External Links:
 
Xenbase Gene ID XB-GENE-22063677 XB-GENE-22063678 XB-GENE-6254179
Gene Symbol ptpn11 ptpn11.L ptpn11.S
Chromosome chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.2
CDS Gene model
Entrez Gene 399291
mRNA RefSeq
Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ptpn11 ptpn11.L ptpn11.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PTPN11 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ptpn11 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ptpn11 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR ptpn11b ptpn11a ZFIN Ensembl
chicken
GEISHA PTPN11 Ensembl
fruit fly
worm
Publications
First Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells., EMBO J 1984  
Most Recent A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway., Front Physiol 2019                    
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 0 term 2 terms
PANTHER ptpn11
KEGG Pathways K07293
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks
Antibodies Ptpn11 Ab1
ORFs ptpn11.S ORF1
Clones Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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