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Summary Expression Gene Literature (101) GO Terms (27) Nucleotides (147) Proteins (45) Interactants (516) Wiki
XB-GENEPAGE-6072919
Gene Symbol:
pdgfra

Gene Name:
platelet-derived growth factor receptor, alpha polypeptide

Synonyms:
pdgfr-alpha , pdgfr2 , pdgfralpha ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotax...[+]



Interactants:
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Diseases: 


Disease Ontology:
gastrointestinal stromal tumor

OMIM:
GASTROINTESTINAL STROMAL TUMOR; GIST [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-6072920 XB-GENE-6072934 XB-GENE-17335238
Gene Symbol pdgfra pdgfra.L pdgfra.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100124862
380245
108706592
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pdgfra pdgfra.L pdgfra.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PDGFRA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pdgfra MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pdgfra Ensembl
zebrafish
ZFIN, AGR pdgfra ZFIN Ensembl
chicken
GEISHA PDGFRA Ensembl
fruit fly
worm
Publications
First Molecular cloning of tyrosine kinases in the early Xenopus embryo: identification of Eck-related genes expressed in cranial neural crest cells of the second (hyoid) arch., Dev Dyn 1995                    
Most Recent Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads., Differentiation 2018                            
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 8 terms 6 terms
PANTHER pdgfra
KEGG Pathways K04363 K04363 K04363
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pdgfra
Antibodies pdgfra Ab2 pdgfra Ab2 pdgfra Ab2
Morpholinos pdgfra MO1 pdgfra MO1 pdgfra MO1
ORFs pdgfra.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list