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Summary Expression Gene Literature (3) GO Terms (16) Nucleotides (204) Proteins (20) Interactants (71) Wiki
XB-GENEPAGE-5879486
Gene Symbol:
mkrn2

Gene Name:
makorin ring finger protein 2

Synonyms:
rnf62 , makorin-2 ( Add synonyms , Nomenclature history )

Gene Function:
E3 ubiquitin ligase

Protein Function :
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidy...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5879487 XB-GENE-6079172 XB-GENE-17331626
Gene Symbol mkrn2 mkrn2.L mkrn2.S
Chromosome scaffold_1680 Scaffold24
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 4.1 Version 9.2
CDS Gene model
Entrez Gene 448038
735181
mRNA RefSeq RefSeq
Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mkrn2 mkrn2.L mkrn2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MKRN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mkrn2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mkrn2 Ensembl
zebrafish
ZFIN, AGR mkrn2 ZFIN Ensembl
chicken
GEISHA MKRN2 Ensembl
fruit fly
worm
Publications
First Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal., J Biol Chem 2008  
Most Recent An in vivo screen to identify candidate neurogenic genes in the developing Xenopus visual system., Dev Biol 2015                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 2 terms 0 term
PANTHER mkrn2
KEGG Pathways K15687 K15687
KOG [O] Predicted E3 ubiquitin ligase (alt_id KOG:1039)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks
Morpholinos mkrn2 MO1 , mkrn2 MO2 , mkrn2 MO3 mkrn2 MO1 , mkrn2 MO2 , mkrn2 MO3 mkrn2 MO1 , mkrn2 MO2 , mkrn2 MO3
ORFs mkrn2 ORF1 mkrn2.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

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