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Summary Expression Gene Literature (3) GO Terms (11) Nucleotides (195) Proteins (16) Interactants (71) Wiki
XB-GENEPAGE-5879486
Gene Symbol: mkrn2

Gene Name: makorin ring finger protein 2

Synonyms: rnf62 , makorin-2 ( Add synonyms , Nomenclature history )

Gene Function: E3 ubiquitin ligase

Protein Function :
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidy...[+]


Interactants: Loading ...
 
Xenbase Gene ID XB-GENE-5879487 XB-GENE-6079172 XB-GENE-17331626
Gene Symbol mkrn2 mkrn2.L mkrn2.S
Chromosome scaffold_1680 Scaffold24
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS
Entrez Gene: 448038
Entrez Gene: 735181
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mkrn2 mkrn2.L mkrn2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MKRN2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Mkrn2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR mkrn2 ZFIN Ensembl
chicken
GEISHA MKRN2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal., J Biol Chem 2008  
Most Recent An in vivo screen to identify candidate neurogenic genes in the developing Xenopus visual system., Dev Biol 2015                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 2 terms 0 term
PANTHER mkrn2
KEGG Pathways K15687 K15687
KOG [O] Predicted E3 ubiquitin ligase (alt_id KOG:1039)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon
Morpholino mkrn2 MO1 , mkrn2 MO2 , mkrn2 MO3 mkrn2 MO1 , mkrn2 MO2 , mkrn2 MO3 mkrn2 MO1 , mkrn2 MO2 , mkrn2 MO3
ORF mkrn2 ORF1 mkrn2.L ORF1
Affymetrix 1.0 Str.24743.1.S1_at Xl.16155.1.A1_at
Affymetrix 2.0 Xl2.16155.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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