Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (112) GO Terms (9) Nucleotides (27) Proteins (13) Interactants (104) Wiki
XB-GENEPAGE-6084576

Gene Symbol: kcnj11

Gene Name: potassium channel, inwardly rectifying subfamily J, member 11

Synonyms: hhf2 , phhi , ikatp , tndm3 , kir6.2 ( Add Xenopus synonyms , Nomenclature history )

Gene Function: Inward rectifier K+ channel

Protein Function :

Interactants: Loading ...
Disease Ontology: transient neonatal diabetes mellitus [+]

OMIM Diseases: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]

 
Xenbase Gene ID XB-GENE-6084577 XB-GENE-17340813 XB-GENE-17340814
Gene Symbol kcnj11 kcnj11.L kcnj11.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
mRNA NCBI Nucleotide
Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine kcnj11 kcnj11.L kcnj11.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KCNJ11 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Kcnj11 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR kcnj11 ZFIN Ensembl
chicken
GEISHA KCNJ11 Ensembl
fruit fly
worm
WORMBASE
Publications
First Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator., Proc Natl Acad Sci U S A 1996  
Most Recent Permanent neonatal diabetes: combining sulfonylureas with insulin may be an effective treatment., Diabet Med 2018  
All View All Papers 1 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 0 term 0 term
PANTHER kcnj11
KEGG Pathways
KOG [P] Inward rectifier K+ channel
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Kcnj11 Ab1
Affymetrix 1.0 StrEns.7988.1.S1_at
Affymetrix 2.0

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.2


Major funding for Xenbase is provided by grant P41 HD064556