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Summary Expression Gene Literature (188) GO Terms (19) Nucleotides (187) Proteins (66) Interactants (1905) Wiki
Gene Symbol: pax3

Gene Name: paired box 3

Synonyms: pax-3 , Waardenburg syndrome 1 , xpax3 , pax3-a , pax3-b , ws1 , cdhs , hup2 ( Add synonyms , Nomenclature history )

Gene Function: paired box transcription factor with homeodomain

Protein Function :
Probable transcription factor. Promotes both hatching gland and neural crest cell fates, two of the cell populations that arise from the neural plate border. Acts downstream of msx1 to induce the neura...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: Waardenburg syndrome type 1 [+]


External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-482740 XB-GENE-6252072 XB-GENE-482744
Gene Symbol pax3 pax3.L pax3.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448464
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot TrEMBL TrEMBL RefSeq TrEMBL TrEMBL Swiss-Prot RefSeq TrEMBL TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pax3 pax3.L pax3.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards PAX3 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Pax3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR ZFIN, AGR pax3a pax3b ZFIN Ensembl
fruit fly
First Primitive streak mesoderm-like cell lines expressing Pax-3 and Hox gene autoinducing activities., Development 1994  
Most Recent Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction., Dev Biol 2020          
All View All Papers 53 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 15 terms 15 terms
KEGG Pathways K09381 K09381 K09381
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pax3
Mutants Xla.pax3emHorb
Antibodies Pax3 Ab1 Pax3 Ab1 Pax3 Ab1
Transgenes Tg(pax3:eGFP) , Tg(pax3:Katushka;cryga:Venus,GFP) Tg(pax3:eGFP) , Tg(pax3:Katushka;cryga:Venus,GFP) Tg(pax3:eGFP) , Tg(pax3:Katushka;cryga:Venus,GFP)
Morpholinos pax3 MO1 , pax3 MO2 , pax3 MO3 , pax3 MO4 pax3 MO1 , pax3 MO2 , pax3 MO3 , pax3 MO4 pax3 MO1 , pax3 MO2 , pax3 MO3 , pax3 MO4
ORFs pax3 ORF1 pax3.L ORF1 pax3.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience EXRC Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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