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Summary Expression Gene Literature (13) GO Terms (26) Nucleotides (84) Proteins (30) Interactants (146) Wiki
XB-GENEPAGE-977138
Gene Symbol: chrna1

Gene Name: cholinergic receptor, nicotinic alpha 1

Synonyms: achra , achrd , chrna , cms2a , fccms , sccms , chrna1-a , chrna1-b , nAChR-a1 ( Add synonyms , Nomenclature history )

Gene Function: acetylcholine receptor

Protein Function :
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Interactants: Loading ...
Disease Ontology: multiple pterygium syndrome [+]

OMIM Diseases: MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE; LMPS [+]

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Xenbase Gene ID XB-GENE-977139 XB-GENE-977144 XB-GENE-6252266
Gene Symbol chrna1 chrna1.L chrna1.S
Chromosome Chr09 Scaffold43242 Scaffold136
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein TrEMBL RefSeq TrEMBL TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine chrna1 chrna1.L chrna1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CHRNA1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Chrna1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR chrna1 ZFIN Ensembl
chicken
GEISHA CHRNA1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Regulation of acetylcholine receptor transcript expression during development in Xenopus laevis., J Cell Biol 1988                
Most Recent Genomic Takeover by Transposable Elements in the Strawberry Poison Frog., Mol Biol Evol 2018                
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 25 terms 6 terms 5 terms
PANTHER chrna1
KEGG Pathways K04803 K04803 K04803
KOG [T] Acetylcholine receptor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Fluoro-BT Ab Fluoro-BT Ab Fluoro-BT Ab
ORF chrna1.L ORF1
Affymetrix 1.0 Str.29602.1.A1_s_at [+] Xl.1118.1.S1_at [+] Xl.1117.1.S1_at
Affymetrix 2.0 Xl2.1118.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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