Gene Symbol: ventx2.1 [provisional] Gene Name: VENT homeobox 2, gene 1 [provisional] Synonyms: Xbr-1a, xvent-2b, vox1, Xvr-11b, xvent-2 Add Xenopus synonyms Gene Function: homeodomain transcription factor Interactants: ventx2.2(35) , bmp4(22) , gsc(14) , ventx1.1(12) , smad1(11) , chrd(10) , ventx1.2(10) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_203531|Xenopus (Silurana) tropicalis vent-2 (LOC394456), mRNA CACATAATGAACACAAGGACTACTACAGGAAAGATGACCAAAGCTTTCTCTTCAGTAGAATGGCTTGCCCAAAGCAGCCGGAGATCTCACAAAGAGCAGCCCAGCAAAGGGGATCAGCGATATTCACCGTACCCAAGCCCATCCCTGCCTTCCTGGAACAGTGATGTGTCCCCTTCTTCATGGAACAGCCAGCTGTCTCCAGTTGCAGGCAGTGCCCAAGTCTCACCGTGCCCTGGGAGTGCACAATATTCCTCAGACAGTGAATTATCTCTCTATTCCAATGAAGATGAAGACTTATTCTGTGAAAAGGACCTTAATACCCCTTCTACCCCTGGGGACAATGGATTGCTACACAGGGACACAGCCACACATGAGTACTCTGGAATGGTTTCAGTGCCAGCAAATACTCCCAGAACCACTTCCAATGAAGATGCTGCTAAGTCTGGCTACAGCACTAGCACTGACTCAGGCTATGAAAGTGAAGCAAGTCGCTCCAGCTCTACAGCCCCTGAAGGAGATGCCACCGTATCCCTGAGCCCCAATGATACTTCAGATGAAGAGGGCAAGTTGGGCCGAAGGTTGCGAACAGCTTTCACCAGTGATCAGATCTCCACTCTGGAGAAGACTTTTCAGAAACACAGATACCTTGGGGCTTCTGAGAGACGGAAACTCGCAGCCAAACTCCAGCTTTCTGAAGTCCAGATTAAAACCTGGTTCCAGAACCGCAGGATGAAATACAAACGGGAAATCCAAGATGGCAGACCTGACTCATACCACCCAGCCCAGTTCTTTGGTGTGTACGGCTATTCACAGCAGCCCACTCCTGTATTCCAACATGCAGTGCAACAACCCTACCCAGGTTATAGCCCACTAATGGAAACCCTGCCTGGCACCATGCCCTATGCCATGCACCCCCCTGCCATGGACTCTCTGAATCATTTCAACTCTCCACCTTTTCAAATGTTCTACATGCCCCAACAGCACCTTGGGCAGCCTCTGGCCTACTAAGAAGGGCCTAAGATTGGCTGTTTGTTAGCTATTAGCCTGACGCCAATTCAAAGGTCTAAACCAAACCAAAGACTGGACTTTTCCATGGGCTACTATTCTCCCATAGGACATAATAAATGCACTAGAAATCGCTATTGGCGAGATGTTTACAGAATTGCTGGCTACTATTGGGCCATGTGTAATGTTATTTACATGATTTTATTCACATTGAATAATATATTGTCTATTCTATGAGTAATAACATTTATAATAAATGTAAGTAATATTTAAAAAAA	Refseq >NM_001088138|Xenopus laevis VENT-2 transcription factor (LOC397948), mRNA AGAACACAAGGACTAATACAGACAAGATGACTAAAGCTTTCTCCTCTGTTGAATGGCTTGCTCAAAGCAGCCGCAGATCTCACAGAGAGCAGCCAAGCAAAGTGGATCAGAGATATTCACCGTACCCCAGGCCATCCCTGCCTTCCTGGAACAGTGATGTGTCCCCTTCTTCATGGAACAGCCAACTATCTCCAGATCCAGACAGTGCCCAAGTCTCACCATGCCCTGTGAGTGCACAAGTATCTCCATATTCCTCAGACAGTGAAATATCACTGTATTCACATGAAGAAGAAGCCTCTTTCTATGGAATGGACTTTAATACATCATCATCCCCTGGAGACAATGGATTGCTACACAGGGACACAACCTCATACTCCAGAGGAATGGAGGCCATGTCGGCCAGCACTCCAGCAACATCACCTGTGAAAGGGGCACAACCTGTTGATTCCGCCTACAGCACTAGCACTGACTCAGGCTATGAAAGTGAAACGAGTCGATCCAACTCTACAGCCCCTGAAGGAGATGCCTCCGTATCTCTGAGTCCCAATGATACCTCAGATGAAGAGGGCAAGATGGGCCGAAGGTTGAGGACGGCTTTCACCAGTGATCAGATCTCCACTCTGGAGAAGACTTTTCAGAAACACAGATACCTTGGGGCGTCTGAAAGACGGAAACTCGCAGCCAAACTCCAGCTTTCTGAAGTCCAGATTAAAACTTGGTTCCAGAACCGCAGGATGAAATACAAACGGGAAATCCAAGATGGCAGACCAGACTCATACCACCCAGCCCAGTTCTTTGGTGTGTACGGCTATGCACAGCAGCCCACTCCTGTATTCCAGCATGCAGTCCAACATCCCTACCCAGGTTATAACCCACTAATGGAAACCCTGCCTGGTACCATGCCCTATACCATGCATCCACCTGCCATGGACTCTCTGACTCCCTTCAACTCTCAACCTTTTCAGATGCTCTACCTGCCCCAACAGCACCTTGGGCAACCTCTGGCCTATTAGGAAGAAAGGCCATTTGTTAGATATTAATCTAGAACTTATAAAAGGACTATACTAAAGGCTGGACTTTTCCATGGACTTCTGTCCTCCCGCAGGACAAACAAAATTGCACTGAATATTGTTATTGACAAGATGTTTACTGAATGGATGGCTAATATTGGGCCATGTGTTGACATGATTTTATTCACATTGAATAGTGGCGTGTATATTCTATGAAAAATACCATTTATATGACTAATAAATGTAAGTTATATTTAAAAAAAAAAAAAAA		Refseq >NM_001087981|Xenopus laevis Xbr-1b protein (xbr-1b), mRNA CGGTGAAGATGACCAAAGCTTTCTCCTCAGTAGAATGGCTTGCTCAAAGCAGCCGCAGATCTTACAGAGAAAAGCCAAGCAAAGTGGATCAGCGATATTCACCGTACCCAAGCCCATCCCTGCCTTCCTGGAACAGTGAAGTATCCCCTTCTTCATGGAACAACCAACTATCTCGAGATCCAGACAGTGCCCAAGTCTCACCATGTCCTGGGAATGCACAAGTATCTCCATATTCCTCAGACAGTGAAATATCACTGTATTCCCATGAAGAAGAAACCACATTCCATGGAAGGGACCTTAATACCTCAACCCCTGGAGACAATGGATTTCTACACAGGGACACAACCACATATTACAGAGGAATGGAGACCTTGCCAGCCAGCACTCCAGCAACATCACCTGTGAAAGGGGCACAATCTGTTGATTCCGGCTACAGCACTAGCACTGACTCCGACTATGAAAGTGAAGCAAGTCGCTCCAGCTCTGCAGCCCCTGAAGGAGATGCCACCATGTCTCTGAGCCCCAGTGATACCTCAGATGAAGAGGGCAAGATGGGCCGAAGGCTGAGAACAGCTTTCACCAGTGATCAGATCTCCACTCTGGAGAAGACTTTCCAGAAACACAGATACCTTGGGGCATCTGAAAGGCGTAAACTCGCAGCCAAACTCCAGCTTTCTGAAGTCCAGATTAAAACCTGGTTTCAGAACCGCAGGATGAAATACAAACGGGAAATTCAAGATGGCAGACCAGACTCATACCACCCAGCCCAGTTCTTTGGTGTGTACGGCTATTCACAGCAGCCAACTCCTGTATTCCAGCATGCAGTACAACAACCTTACCCAGGTTATAACCCACTAATGGAATCCATGCCTTGCACCATGCCCTATGCCATGCATCCTCCTGCCATGGACTCCCTGAGTCCCTTCAACTCCCAGCCTTTCCAGATGCTCTACTTGCCCCAACAGCACCTTGGGCAGCCCCTGTTCTTCCAGGAAGAAAGGCCATTTGTAAGATATTAATCTGAAGCTATTGAAAGGACTATACTAAAGGCTGGACTTTTCATGGACTTCTGTTCTTCCACAGGACAAAAAATTGCACTGAATGTTGCTATTGGCAAGATGATTACAGAATAGCTGGCTACTATTGGCCTATTTGTTATGTATCTTTACATGATTTTATTCACATTGAATATTGAAGTGTATATTCTATGAGTAATACCATTTGTATGACTAATAAATGTAAGTTATATTTAAAAAAAAAAAAAAAAACG
Protein		Refseq >NP_988862|vent-2 [Xenopus (Silurana) tropicalis] MNTRTTTGKMTKAFSSVEWLAQSSRRSHKEQPSKGDQRYSPYPSPSLPSWNSDVSPSSWNSQLSPVAGSAQVSPCPGSAQYSSDSELSLYSNEDEDLFCEKDLNTPSTPGDNGLLHRDTATHEYSGMVSVPANTPRTTSNEDAAKSGYSTSTDSGYESEASRSSSTAPEGDATVSLSPNDTSDEEGKLGRRLRTAFTSDQISTLEKTFQKHRYLGASERRKLAAKLQLSEVQIKTWFQNRRMKYKREIQDGRPDSYHPAQFFGVYGYSQQPTPVFQHAVQQPYPGYSPLMETLPGTMPYAMHPPAMDSLNHFNSPPFQMFYMPQQHLGQPLAY	Refseq >NP_001081607|VENT-2 transcription factor [Xenopus laevis] MTKAFSSVEWLAQSSRRSHREQPSKVDQRYSPYPRPSLPSWNSDVSPSSWNSQLSPDPDSAQVSPCPVSAQVSPYSSDSEISLYSHEEEASFYGMDFNTSSSPGDNGLLHRDTTSYSRGMEAMSASTPATSPVKGAQPVDSAYSTSTDSGYESETSRSNSTAPEGDASVSLSPNDTSDEEGKMGRRLRTAFTSDQISTLEKTFQKHRYLGASERRKLAAKLQLSEVQIKTWFQNRRMKYKREIQDGRPDSYHPAQFFGVYGYAQQPTPVFQHAVQHPYPGYNPLMETLPGTMPYTMHPPAMDSLTPFNSQPFQMLYLPQQHLGQPLAY		Refseq >NP_001081450|Xbr-1b protein [Xenopus laevis] MTKAFSSVEWLAQSSRRSYREKPSKVDQRYSPYPSPSLPSWNSEVSPSSWNNQLSRDPDSAQVSPCPGNAQVSPYSSDSEISLYSHEEETTFHGRDLNTSTPGDNGFLHRDTTTYYRGMETLPASTPATSPVKGAQSVDSGYSTSTDSDYESEASRSSSAAPEGDATMSLSPSDTSDEEGKMGRRLRTAFTSDQISTLEKTFQKHRYLGASERRKLAAKLQLSEVQIKTWFQNRRMKYKREIQDGRPDSYHPAQFFGVYGYSQQPTPVFQHAVQQPYPGYNPLMESMPCTMPYAMHPPAMDSLSPFNSQPFQMLYLPQQHLGQPLFFQEERPFVRY

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.4932	Xl.699 [+] Xl.82907		Xl.366 [+] Xl.32193
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		17 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human
mouse
zebrafish

Publications
First:		The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling [correction of controling] dorsoventral patterning of Xenopus mesoderm. [Development 1996]
Most recent:		Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling. [Dev Cell 2012]
		View All Papers 7 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[R] Transcription factor BarH and related HOX domain proteins

Reagents		tropicalis	laevis a		laevis b
Clones		EXRC - 2 clone(s)
		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.4932.1.S1_a_at	Xl.699.1.S1_at [+] Xl.699.1.S1_s_at		Xl.366.1.S1_x_at
Affymetrix 2.0			Xl2.699.1.S1_s_at [+] Xl2.699.1.S1_x_at		Xl2.366.1.S1_at

Symbol legend[+]

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   - Literature Or Expression Images